AutismKB 2.0

Annotation Detail for MTOR


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Basic Information Top
Gene Symbol:MTOR ( FLJ44809,FRAP,FRAP1,FRAP2,RAFT1,RAPT1 )
Gene Full Name: mechanistic target of rapamycin (serine/threonine kinase)
Band: 1p36.22
Quick LinksEntrez ID:2475; OMIM: 601231; Uniprot ID:MTOR_HUMAN; ENSEMBL ID: ENSG00000198793; HGNC ID: 3942
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
567Phosphoserine.
916Phosphoserine.
1162Phosphothreonine.
1218N6-acetyllysine.
1261Phosphoserine.
1829Phosphothreonine.
1839Phosphothreonine.
1840Phosphothreonine.
1841Phosphothreonine.
1843Phosphoserine.
1847Phosphoserine.
1849Phosphoserine.
1851Phosphoserine.
1856Phosphothreonine.
1859Phosphoserine.
1863Phosphoserine.
2448Phosphoserine.
2449Phosphotyrosine.
2471Phosphothreonine.
2478Phosphoserine.
2481Phosphoserine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004958
  • Location:chr1 11089179-11245150
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 11244876 11245858 982 217
Fos K562GSE19551 11244852 11245894 1042 223
GABP k562GSE8489 11245206 11245768 562 337
H3ac HepG2E 11245242 11245768 526 355
P300 T30-glioblastomaGSE21026 11244866 11245655 789 110
PHF8 293TGSE20725 11244685 11245727 1042 56
PHF8 HeLaGSE20725 11244563 11246024 1461 143
TAFII hESGSE17917 11245027 11245684 657 205
p130 SenescentGSE19898 11245146 11245686 540 266
p130 shRbSenescentGSE19898 11244923 11245657 734 140
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 11224334 11224642 308 0
CTCF CD4SISSRdata 11224334 11224642 308 0
CTCF JurkatGSE12889 11224307 11224688 381 0
ER E2-MCF7GSE14664 11156352 11156394 42 0
FoxA1 MCF7MACSdata 11103853 11104031 178 0
GABP k562GSE8489 11244131 11244634 503 0
H3K4me3 colorectalcancer 11244131 11244740 609 0
H3ac HepG2E 11244131 11244837 706 0
NRSF mAbJurkat 11179538 11179842 304 0
Nanog ESGSE20650 11224244 11224649 405 0
Oct1 H2O2-HelaGSE14283 11170441 11170470 29 0
Oct1 H2O2-HelaGSE14283 11171250 11171282 32 0
Oct1 H2O2-HelaGSE14283 11217714 11217741 27 0
Oct1 H2O2-HelaGSE14283 11222570 11222607 37 0
Oct1 HelaGSE14283 11100838 11100903 65 0
Oct1 HelaGSE14283 11118984 11119026 42 0
Oct1 HelaGSE14283 11156357 11156391 34 0
Oct1 HelaGSE14283 11171251 11171280 29 0
Oct1 HelaGSE14283 11217712 11217740 28 0
Oct1 HelaGSE14283 11222570 11222606 36 0
PHF8 Hs68minusFBSGSE20725 11244650 11245621 971 0
RARA MCF7GSE15244 11116718 11117790 1072 0
hScc1 BcellGSE12603 11224096 11224381 285 0
hScc1 BcellGSE12603 11233577 11233916 339 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
194 EST chr1 11138746 11143860 89 mRNA FRAP1 chr1 11100857 11256830Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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