AutismKB 2.0

Annotation Detail for ALPPL2


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Basic Information Top
Gene Symbol:ALPPL2 ( ALPG,ALPPL,GCAP )
Gene Full Name: alkaline phosphatase, placental-like 2
Band: 2q37.1
Quick LinksEntrez ID:251; OMIM: 171810; Uniprot ID:PPBN_HUMAN; ENSEMBL ID: ENSG00000163286; HGNC ID: 441
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
141N-linked (GlcNAc...) (Potential).
268N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
141N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
268N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
503GPI-anchor amidated aspartate (Bysimilarity).Swiss-Prot 53.0
Location(AA) Modification Resource
103Phosphoserine(PKC)HMM predict
141N-linkedHMM predict
146N-linkedHMM predict
174Phosphoserine(CDC2)HMM predict
236SulfotyrosineHMM predict
240Phosphotyrosine(INSR)HMM predict
240SulfotyrosineHMM predict
241Phosphoserine(IKK)HMM predict
268N-linkedHMM predict
302Phosphothreonine(PKC)HMM predict
344Phosphotyrosine(EGFR)HMM predict
371Phosphoserine(CK1)HMM predict
418Phosphotyrosine(INSR)HMM predict
431Phosphoserine(CK2)HMM predict
433Phosphoserine(CK2)HMM predict
433Phosphoserine(ATM)HMM predict
501Phosphothreonine(PKC)HMM predict
510O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_031313
  • Location:chr2 232979796-232983660
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 232978908 232980219 1311 233
hScc1 BcellGSE12603 232978868 232979650 782 538
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF JurkatGSE12889 232993729 232993867 138 10138
CTCF G2GSE9613 232983805 232983993 188 239
CTCF G2GSE9613 232991874 232992089 215 8321
CTCF G2GSE9613 232992408 232994344 1936 9716
CTCF G2GSE9613 232995128 232995366 238 11587
hScc1 BcellGSE12603 232991700 232992475 775 8427
hScc1 BcellGSE12603 232993585 232994095 510 10180
hScc1 G2GSE9613 232992561 232994131 1570 9686
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 232980586 232982802 2216 0
hScc1 BcellGSE12603 232982505 232982921 416 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018