AutismKB 2.0

Annotation Detail for FUS


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Basic Information Top
Gene Symbol:FUS ( ALS6,FUS1,HNRNPP2,POMP75,TLS )
Gene Full Name: fused in sarcoma
Band: 16p11.2
Quick LinksEntrez ID:2521; OMIM: 137070; Uniprot ID:FUS_HUMAN; ENSEMBL ID: ENSG00000089280; HGNC ID: 4010
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
216Omega-N-methylated arginine.
218Omega-N-methylated arginine.
277Phosphoserine.
286Phosphothreonine.
346Phosphoserine.
Location(AA) Modifications Resource
216Omega-N-methylated arginine.Swiss-Prot 53.0
218Omega-N-methylated arginine.Swiss-Prot 53.0
257Phosphoserine (PKC beta)Phospho.ELM 6.0
Location(AA) Modification Resource
11O-linkedHMM predict
25Phosphotyrosine(Abl)HMM predict
26Phosphoserine(ATM)HMM predict
30Phosphoserine(ATM)HMM predict
33Phosphotyrosine(Abl)HMM predict
39Phosphoserine(CK1)HMM predict
47O-linkedHMM predict
56Phosphoserine(CK1)HMM predict
61Phosphoserine(ATM)HMM predict
70O-linkedHMM predict
84Phosphoserine(ATM)HMM predict
89Phosphoserine(CK1)HMM predict
100SulfotyrosineHMM predict
107O-linkedHMM predict
107Phosphoserine(CK1)HMM predict
108Phosphoserine(IKK)HMM predict
108O-linkedHMM predict
109O-linkedHMM predict
109Phosphothreonine(PKC)HMM predict
115Phosphoserine(CDK)HMM predict
117O-linkedHMM predict
117Phosphoserine(ATM)HMM predict
120Phosphoserine(CK1)HMM predict
122Phosphotyrosine(Abl)HMM predict
129Phosphoserine(IKK)HMM predict
131Phosphoserine(ATM)HMM predict
149Phosphotyrosine(Syk)HMM predict
155Phosphotyrosine(Abl)HMM predict
162N-linkedHMM predict
177Phosphotyrosine(Abl)HMM predict
185Phosphoserine(CK1)HMM predict
194Phosphotyrosine(INSR)HMM predict
208Phosphotyrosine(INSR)HMM predict
208Phosphotyrosine(Abl)HMM predict
216MethylarginineHMM predict
218MethylarginineHMM predict
233N-linkedHMM predict
239Phosphotyrosine(Syk)HMM predict
239Phosphotyrosine(INSR)HMM predict
242MethylarginineHMM predict
244MethylarginineHMM predict
251MethylarginineHMM predict
259MethylarginineHMM predict
282Phosphoserine(CK2)HMM predict
284N-linkedHMM predict
285N-linkedHMM predict
295N-linkedHMM predict
340Phosphoserine(IKK)HMM predict
386MethylarginineHMM predict
394MethylarginineHMM predict
397Phosphotyrosine(INSR)HMM predict
407MethylarginineHMM predict
430N-linkedHMM predict
435N-linkedHMM predict
437N-linkedHMM predict
442N-linkedHMM predict
476MethylarginineHMM predict
479Phosphotyrosine(INSR)HMM predict
485MethylarginineHMM predict
487MethylarginineHMM predict
491MethylarginineHMM predict
495MethylarginineHMM predict
498MethylarginineHMM predict
503MethylarginineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-197 hsa-mir-197 1 19671678
hsa-miR-198 hsa-mir-198 0 19671678
hsa-miR-93 hsa-mir-93 7 19671678
hsa-miR-93* hsa-mir-93 7 19671678
hsa-miR-98 hsa-mir-98 X 19671678
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018