Annotation Detail for FUT4

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Basic Information Top

Gene Symbol:	FUT4 ( CD15,ELFT,FCT3A,FUC-TIV,FUTIV,LeX,SSEA-1 )
Gene Full Name:	fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
Band:	11q21
Quick Links	Entrez ID:2526; OMIM: 104230; Uniprot ID:FUT4_HUMAN; ENSEMBL ID: ENSG00000196371; HGNC ID: 4015
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:2 results
Experimental PTM Sites from dbPTM:2 results
Predicted PTM Sites by profile HMM from dbPTM:13 results

Location(AA)	Modification
216	N-linked (GlcNAc...) (Potential).
315	N-linked (GlcNAc...) (Potential).

Location(AA)	Modification	Resource
57	Phosphoserine(CDK)	HMM predict
59	Phosphothreonine(CDK)	HMM predict
59	Phosphothreonine(MAPK)	HMM predict
59	Phosphothreonine(CDC2)	HMM predict
91	N-linked	HMM predict
157	O-linked	HMM predict
159	Phosphoserine(CDK)	HMM predict
159	O-linked	HMM predict
159	Phosphoserine(CDC2)	HMM predict
190	N-linked	HMM predict
219	O-linked	HMM predict
219	Phosphoserine(IKK)	HMM predict
226	O-linked	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_002033
Location:chr11 93916774-93922710
strand:+

Upstream the gene:4 results
Downstream the gene:2 results
Inside the gene:7 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
FOXA1	DLD1	GSE12801	93912248	93912564	316	4369
Oct1	Hela	GSE14283	93907182	93907253	71	9557
p130	Quiescent	GSE19898	93916554	93916869	315	63
p130	shRbQuiescent	GSE19898	93916418	93917007	589	62

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
Oct1	Hela	GSE14283	93923946	93923987	41	1256
Oct1	Hela	GSE14283	93925561	93925589	28	2865

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ER	MCF7	GSE19013	93916785	93917348	563	0
NRSF	pAb	Jurkat	93917638	93917992	354	0
PHF8	HeLa	GSE20725	93916375	93918850	2475	0
PHF8	Hs68plusFBS	GSE20725	93916451	93917564	1113	0
p130	Senescent	GSE19898	93916462	93917116	654	0
p130	shRbSenescent	GSE19898	93916540	93917035	495	0
p130	shRbSenescent	GSE19898	93917144	93917309	165	0

Validated miRNA targets

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
5050	mRNA	FUT4	chr11	93916774	93922712	821	mRNA	FUT4	chr11	93915778	93917595	Sense/Antisense (SA) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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