AutismKB 2.0

Annotation Detail for NEIL2


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Basic Information Top
Gene Symbol:NEIL2 ( FLJ31644,MGC2832,MGC4505,NEH2,NEI2 )
Gene Full Name: nei endonuclease VIII-like 2 (E. coli)
Band: 8p23.1
Quick LinksEntrez ID:252969; OMIM: 608933; Uniprot ID:NEIL2_HUMAN; ENSEMBL ID: ENSG00000154328; HGNC ID: 18956
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
50N6-acetyllysine.
154N6-acetyllysine.
Location(AA) Modifications Resource
50N6-acetyllysine.Swiss-Prot 53.0
154N6-acetyllysine.Swiss-Prot 53.0
Location(AA) Modification Resource
67O-linkedHMM predict
68Phosphoserine(CDC2)HMM predict
70O-linkedHMM predict
70Phosphothreonine(CDK)HMM predict
70Phosphothreonine(CDC2)HMM predict
70O-linkedHMM predict
117Phosphotyrosine(Syk)HMM predict
187Phosphoserine(CDC2)HMM predict
187O-linkedHMM predict
191O-linkedHMM predict
315CysteineHMM predict
329S-farnesylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_145043
  • Location:chr8 11664665-11682262
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NFkBII GM10847GSE19485 11662889 11665096 2207 673
NFkBII GM12892GSE19485 11663091 11665418 2327 411
PHF8 293TGSE20725 11664216 11665050 834 33
p130 shRbSenescentGSE19898 11664324 11664702 378 153
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 11684088 11684707 619 2135
ER MCF7GSE19013 11684281 11685292 1011 2524
TFAP2C MCF7GSE21234 11682939 11683237 298 826
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 11664400 11665035 635 0
CTCF G2GSE9613 11665538 11665951 413 0
CTCF G2GSE9613 11680834 11681186 352 0
ER Breast-CancerGSE22609 11672886 11673240 354 0
H3ac HepG2E 11665254 11665740 486 0
Oct1 HelaGSE14283 11671421 11671458 37 0
PHF8 HeLaGSE20725 11664006 11665434 1428 0
RUNX JurkatGSE17954 11677608 11678166 558 0
hScc1 BcellGSE12603 11664333 11665138 805 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018