AutismKB 2.0

Annotation Detail for FZD2


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Basic Information Top
Gene Symbol:FZD2 ( - )
Gene Full Name: frizzled homolog 2 (Drosophila)
Band: 17q21.31
Quick LinksEntrez ID:2535; OMIM: 600667; Uniprot ID:FZD2_HUMAN; ENSEMBL ID: ENSG00000180340; HGNC ID: 4040
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
53N-linked (GlcNAc...) (Potential).
154N-linked (GlcNAc...) (Potential).
548Lys-Thr-X-X-X-Trp motif, mediates
565PDZ-binding.
Location(AA) Modifications Resource
53N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
154N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
53N-linkedHMM predict
59N-linkedHMM predict
110S-palmitoylHMM predict
154N-linkedHMM predict
165O-linkedHMM predict
179Phosphothreonine(CDC2)HMM predict
192Phosphotyrosine(Jak)HMM predict
194Phosphothreonine(PKA)HMM predict
194Phosphothreonine(PKC)HMM predict
209Phosphoserine(PKC)HMM predict
237Phosphoserine(ATM)HMM predict
311Phosphoserine(CK1)HMM predict
315Phosphotyrosine(EGFR)HMM predict
470O-linkedHMM predict
511Phosphothreonine(CDK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001466
  • Location:chr17 39990450-39992432
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 39970880 39971226 346 19398
Fos K562GSE19551 39979870 39980368 498 10332
Fos K562GSE19551 39989773 39990447 674 341
Oct4 hESGSE21916 39972491 39973280 789 17565
p130 shRbQuiescentGSE19898 39989295 39990162 867 722
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF HelaGSE12889 39998834 39999008 174 6489
CTCF JurkatGSE12889 40001893 40001987 94 9508
KLF4 hESGSE17917 40001846 40002022 176 9502
Oct4 hESGSE17917 40001871 40002022 151 9514
hScc1 BcellGSE12603 40012273 40012526 253 19967
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Rb QuiescentGSE19898 39990794 39991047 253 0
hScc1 BcellGSE12603 39990651 39991232 581 0
p130 shRbSenescentGSE19898 39990765 39991092 327 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018