AutismKB 2.0

Annotation Detail for LASS6


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:LASS6 ( CerS6,MGC129949,MGC129950 )
Gene Full Name: LAG1 homolog, ceramide synthase 6
Band: 2q24.3
Quick LinksEntrez ID:253782; OMIM: NA; Uniprot ID:LASS6_HUMAN; ENSEMBL ID: ENSG00000172292; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
18N-linked (GlcNAc...).
Location(AA) Modifications Resource
18N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
18N-linkedHMM predict
182SulfotyrosineHMM predict
195Phosphoserine(ATM)HMM predict
285N-linkedHMM predict
341Phosphoserine(CK1)HMM predict
347Phosphoserine(ATM)HMM predict
347Phosphoserine(CK2)HMM predict
365O-linkedHMM predict
366N-linkedHMM predict
368O-linkedHMM predict
372N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_203463
  • Location:chr2 169021080-169339397
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 169020601 169021291 690 135
Myc hESGSE17917 169020770 169021236 466 78
PHF8 293TGSE20725 169020267 169021242 975 326
TAF k562GSE8489 169019046 169019296 250 1910
TFAP2C MCF7GSE21234 169020420 169021033 613 354
USF1 HepG2E 169019680 169020455 775 1013
hScc1 BcellGSE12603 169020655 169021140 485 183
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 169353131 169353382 251 13859
Oct1 HelaGSE14283 169347481 169347547 66 8117
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 169270345 169270584 239 0
CTCF CD4GSE12889 169323933 169324250 317 0
CTCF CD4GSE12889 169338544 169338685 141 0
CTCF CD4SISSRdata 169270345 169270584 239 0
CTCF CD4SISSRdata 169323933 169324250 317 0
CTCF CD4SISSRdata 169338544 169338685 141 0
CTCF G2GSE9613 169020717 169021555 838 0
CTCF G2GSE9613 169141945 169142629 684 0
CTCF G2GSE9613 169157045 169157249 204 0
CTCF G2GSE9613 169270041 169270357 316 0
CTCF G2GSE9613 169328410 169328606 196 0
CTCF G2GSE9613 169338189 169338768 579 0
ER E2-MCF7GSE14664 169120165 169120235 70 0
ER E2-MCF7GSE14664 169291530 169291566 36 0
ER E2-MCF7GSE14664 169306934 169306967 33 0
ER MCF7GSE19013 169147134 169147769 635 0
FOXA1 MCF7GSE15244 169045351 169045863 512 0
Gata2 K562GSE18868 169338454 169339396 942 0
H3K4me3 colorectalcancer 169021972 169022278 306 0
H3ac HepG2E 169021826 169022416 590 0
KLF4 hESGSE17917 169117303 169117517 214 0
Myc K562GSE19551 169197460 169197844 384 0
Myc K562GSE19551 169228843 169229076 233 0
Myc K562GSE19551 169338325 169339406 1081 0
Nanog ESGSE20650 169117089 169117687 598 0
Nanog ESGSE20650 169226202 169226726 524 0
Nanog hESGSE18292 169226101 169226809 708 0
Oct1 HelaGSE14283 169120177 169120227 50 0
Oct1 HelaGSE14283 169236757 169236828 71 0
Oct1 HelaGSE14283 169289482 169289514 32 0
Oct1 HelaGSE14283 169313312 169313344 32 0
RNAII Tamoxifen-MCF7GSE14664 169222240 169222303 63 0
Rb GrowingGSE19898 169338500 169338775 275 0
Stat6 IL-4-hr1GSE17850 169159555 169160137 582 0
Stat6 IL-4-hr4GSE17850 169338730 169339321 591 0
TAF HelaGSE8489 169128567 169128863 296 0
TAF HelaGSE8489 169290224 169290515 291 0
TAF k562GSE8489 169055102 169055570 468 0
TFAP2C MCF7GSE21234 169035681 169035899 218 0
TFAP2C MCF7GSE21234 169083427 169083862 435 0
TFAP2C MCF7GSE21234 169089837 169090149 312 0
TFAP2C MCF7GSE21234 169203648 169204216 568 0
TFAP2C MCF7GSE21234 169331212 169331698 486 0
hScc1 BcellGSE12603 169055102 169055504 402 0
hScc1 G2GSE9613 169338223 169338803 580 0
p130 shRbQuiescentGSE19898 169148493 169148899 406 0
p63 keratinocytesGSE17611 169040327 169041031 704 0
p63 keratinocytesGSE17611 169089657 169090370 713 0
p63 keratinocytesGSE17611 169148381 169149539 1158 0
p63 keratinocytesGSE17611 169179141 169179957 816 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
15235 mRNA LASS6 chr2 169138341 169456659 2685 mRNA LASS6 chr2 169453970 169468443Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved