AutismKB 2.0

Annotation Detail for XRCC6


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Basic Information Top
Gene Symbol:XRCC6 ( CTC75,CTCBF,G22P1,KU70,ML8,TLAA )
Gene Full Name: X-ray repair complementing defective repair in Chinese hamster cells 6
Band: 22q13.2
Quick LinksEntrez ID:2547; OMIM: 152690; Uniprot ID:XRCC6_HUMAN; ENSEMBL ID: ENSG00000196419; HGNC ID: 4055
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylserine (Potential).
6Phosphoserine; by PRKDC.
27Phosphoserine.
31N6-acetyllysine.
51Phosphoserine; by PRKDC.
222Phosphoserine.
331N6-acetyllysine.
338N6-acetyllysine.
455Phosphothreonine.
461N6-acetyllysine.
468N6-acetyllysine.
520Phosphoserine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001469
  • Location:chr22 40347240-40389997
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
PHF8 293TGSE20725 40346334 40347774 1440 187
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 40392554 40393010 456 2785
CTCF CD4SISSRdata 40392554 40393010 456 2785
CTCF HelaGSE12889 40392615 40392854 239 2737
CTCF JurkatGSE12889 40392502 40393040 538 2774
CTCF G2GSE9613 40392731 40393098 367 2917
FOXA1 MCF7GSE15244 40392731 40393098 367 2917
Myc K562GSE19551 40392484 40393573 1089 3031
PHF8 293TGSE20725 40392424 40393485 1061 2957
PolII HeLaGSE12783 40392559 40393937 1378 3251
RARA MCF7GSE15244 40392926 40393098 172 3015
TFAP2C MCF7GSE21234 40392455 40392973 518 2717
hScc1 BcellGSE12603 40392731 40393098 367 2917
hScc1 CdLSGSE12603 40392731 40393098 367 2917
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 40346644 40348058 1414 0
H3K4me3 colorectalcancer 40347832 40348116 284 0
H3ac HepG2E 40347102 40348235 1133 0
PHF8 Hs68plusFBSGSE20725 40346284 40348302 2018 0
p63 keratinocytesGSE17611 40368700 40369158 458 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
17529 mRNA XRCC6 chr22 40341794 40384552 141 EST chr22 40321378 40341935 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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