AutismKB 2.0

Annotation Detail for ANKK1


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Basic Information Top
Gene Symbol:ANKK1 ( PKK2 )
Gene Full Name: ankyrin repeat and kinase domain containing 1
Band: 11q23.2
Quick LinksEntrez ID:255239; OMIM: 608774; Uniprot ID:ANKK1_HUMAN; ENSEMBL ID: ENSG00000170209; HGNC ID: 21027
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
694Phosphothreonine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
103N-linkedHMM predict
245Phosphoserine(PKG)HMM predict
325Phosphoserine(ATM)HMM predict
359SulfotyrosineHMM predict
364Phosphothreonine(MAPK)HMM predict
496Phosphothreonine(MAPK)HMM predict
515Phosphoserine(ATM)HMM predict
529Phosphothreonine(MAPK)HMM predict
595Phosphothreonine(MAPK)HMM predict
626N-linkedHMM predict
628Phosphothreonine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_178510
  • Location:chr11 112763722-112776348
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 DLD1GSE12801 112760583 112760983 400 2940
P300 T30-glioblastomaGSE21026 112760258 112761084 826 3052
p63 keratinocytesGSE17611 112760406 112761249 843 2895
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER Fulvestrant-MCF7GSE14664 112777851 112777884 33 1519
Oct1 HelaGSE14283 112777850 112777895 45 1524
P300 T0-glioblastomaGSE21026 112777521 112778229 708 1527
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF pAbJurkat 112775831 112776173 342 0
TFAP2C MCF7GSE21234 112773854 112774325 471 0
hScc1 BcellGSE12603 112763770 112764635 865 0
hScc1 BcellGSE12603 112773875 112774107 232 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018