Annotation Detail for PCSK9
Basic Information Top
| Gene Symbol: | PCSK9 ( FH3,HCHOLA3,LDLCQ1,NARC-1,NARC1,PC9 ) |
|---|---|
| Gene Full Name: | proprotein convertase subtilisin/kexin type 9 |
| Band: | 1p32.3 |
| Quick Links | Entrez ID:255738; OMIM: 607786; Uniprot ID:PCSK9_HUMAN; ENSEMBL ID: ENSG00000169174; HGNC ID: 20001 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 47 | Phosphoserine. | |
| 533 | N-linked (GlcNAc...). | |
| 688 | Phosphoserine. | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 47 | Phosphoserine. | Swiss-Prot 53.0 |
| 533 | N-linked (GlcNAc...). | Swiss-Prot 53.0 |
| 688 | Phosphoserine. | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 38 | Sulfotyrosine | HMM predict |
| 38 | Phosphotyrosine(INSR) | HMM predict |
| 38 | Phosphotyrosine(EGFR) | HMM predict |
| 89 | Phosphoserine(ATM) | HMM predict |
| 142 | Sulfotyrosine | HMM predict |
| 171 | Phosphotyrosine(Syk) | HMM predict |
| 221 | Phosphoserine(IKK) | HMM predict |
| 221 | Phosphoserine(PKB) | HMM predict |
| 383 | Phosphoserine(IKK) | HMM predict |
| 386 | Phosphoserine(ATM) | HMM predict |
| 468 | O-linked | HMM predict |
| 595 | Phosphoserine(PKB) | HMM predict |
| 662 | Phosphoserine(IKK) | HMM predict |
| 662 | O-linked | HMM predict |
| 667 | O-linked | HMM predict |
| 668 | O-linked | HMM predict |
| 668 | O-linked | HMM predict |
| 678 | S-palmitoyl | HMM predict |
| 679 | S-palmitoyl | HMM predict |
| 682 | Arginine | HMM predict |
- RefSeq ID: NM_174936
- Location:chr1 55277807-55303110
- strand:+
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| hScc1 | Bcell | GSE12603 | 55271501 | 55271730 | 229 | 6192 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | Hela | GSE12889 | 55309831 | 55310141 | 310 | 6876 |
| CTCF | G2 | GSE9613 | 55308463 | 55308831 | 368 | 5537 |
| CTCF | G2 | GSE9613 | 55309577 | 55310371 | 794 | 6864 |
| Oct1 | H2O2-Hela | GSE14283 | 55310267 | 55310296 | 29 | 7171 |
| Oct1 | Hela | GSE14283 | 55310264 | 55310326 | 62 | 7185 |
| RNAII | Tamoxifen-MCF7 | GSE14664 | 55305171 | 55305261 | 90 | 2106 |
| hScc1 | G2 | GSE9613 | 55309542 | 55310371 | 829 | 6846 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | G2 | GSE9613 | 55277747 | 55278869 | 1122 | 0 |
| CTCF | G2 | GSE9613 | 55286685 | 55286889 | 204 | 0 |
| CTCF | G2 | GSE9613 | 55292679 | 55292959 | 280 | 0 |
| CTCF | G2 | GSE9613 | 55299727 | 55300052 | 325 | 0 |
| CTCF | G2 | GSE9613 | 55302032 | 55302505 | 473 | 0 |
| ER | E2-MCF7 | GSE14664 | 55288726 | 55288758 | 32 | 0 |
| H3ac | HepG2 | E | 55278513 | 55279635 | 1122 | 0 |
| Oct1 | H2O2-Hela | GSE14283 | 55280441 | 55280477 | 36 | 0 |
| Oct1 | Hela | GSE14283 | 55280441 | 55280475 | 34 | 0 |
| RARA | MCF7 | GSE15244 | 55279130 | 55279635 | 505 | 0 |
| TFAP2C | MCF7 | GSE21234 | 55279068 | 55279773 | 705 | 0 |
| hScc1 | Bcell | GSE12603 | 55299804 | 55300469 | 665 | 0 |
Validated miRNA targets