AutismKB 2.0

Annotation Detail for NEGR1


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Basic Information Top
Gene Symbol:NEGR1 ( DMML2433,IGLON4,KILON,MGC46680,Ntra )
Gene Full Name: neuronal growth regulator 1
Band: 1p31.1
Quick LinksEntrez ID:257194; OMIM: 613173; Uniprot ID:NEGR1_HUMAN; ENSEMBL ID: ENSG00000172260; HGNC ID: 17302
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
73N-linked (GlcNAc...) (Potential).
155N-linked (GlcNAc...) (Potential).
187Phosphotyrosine (By similarity).
275N-linked (GlcNAc...) (Potential).
286N-linked (GlcNAc...) (Potential).
294N-linked (GlcNAc...) (Potential).
307N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
73N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
155N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
275N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
286N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
294N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
307N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
324GPI-anchor amidated glycine (Probable).Swiss-Prot 53.0
Location(AA) Modification Resource
11S-palmitoylHMM predict
12S-palmitoylHMM predict
26S-palmitoylHMM predict
73N-linkedHMM predict
116Phosphotyrosine(Jak)HMM predict
155N-linkedHMM predict
163O-linkedHMM predict
187Phosphotyrosine(SRC)HMM predict
187Phosphotyrosine(Syk)HMM predict
187Phosphotyrosine(INSR)HMM predict
204Phosphoserine(CK2)HMM predict
236Phosphothreonine(CDK)HMM predict
236Phosphothreonine(CDC2)HMM predict
236Phosphothreonine(MAPK)HMM predict
275N-linkedHMM predict
286N-linkedHMM predict
294N-linkedHMM predict
295Phosphotyrosine(INSR)HMM predict
307N-linkedHMM predict
313N-linkedHMM predict
317O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_173808
  • Location:chr1 71641213-72520864
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 72522614 72523980 1366 2433
H3K4me3 colorectalcancer 72521256 72522203 947 865
H3K4me3 colorectalcancer 72523007 72523359 352 2319
Oct1 HelaGSE14283 72523982 72524012 30 3133
Oct1 HelaGSE14283 72537832 72537866 34 16985
Oct1 HelaGSE14283 72539318 72539348 30 18469
P300 T30-glioblastomaGSE21026 72521352 72523768 2416 1696
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 71839763 71839796 33 0
ER E2-MCF7GSE14664 72175086 72175122 36 0
ER E2-MCF7GSE14664 72188309 72188395 86 0
ER E2-MCF7GSE14664 72203832 72203865 33 0
ER E2-MCF7GSE14664 72417686 72417721 35 0
ER Fulvestrant-MCF7GSE14664 71839762 71839796 34 0
ER Fulvestrant-MCF7GSE14664 72159463 72159548 85 0
ER Fulvestrant-MCF7GSE14664 72159561 72159639 78 0
ER Fulvestrant-MCF7GSE14664 72188328 72188405 77 0
ER MCF7GSE19013 71686743 71687449 706 0
ER MCF7E 72045482 72045757 275 0
FOXA1 MCF7GSE15244 71699701 71700080 379 0
FoxA1 MCF7MACSdata 71699795 71699920 125 0
FoxA1 MCF7MACSdata 72034457 72034642 185 0
FoxA1 MCF7MACSdata 72156997 72157140 143 0
FoxA1 MCF7MACSdata 72241381 72241643 262 0
H3K27me3 colorectalcancer 72519184 72519829 645 0
H3K27me3 colorectalcancer 72520139 72520462 323 0
H3K4me3 colorectalcancer 72520139 72520462 323 0
KLF4 hESGSE17917 71945253 71945412 159 0
Nanog ESGSE20650 71700348 71701017 669 0
Nanog hESGSE18292 72147293 72147801 508 0
Oct1 H2O2-HelaGSE14283 71661022 71661056 34 0
Oct1 H2O2-HelaGSE14283 71694578 71694613 35 0
Oct1 H2O2-HelaGSE14283 71730410 71730437 27 0
Oct1 H2O2-HelaGSE14283 71763146 71763180 34 0
Oct1 H2O2-HelaGSE14283 71965072 71965110 38 0
Oct1 H2O2-HelaGSE14283 72141675 72141707 32 0
Oct1 H2O2-HelaGSE14283 72203839 72203868 29 0
Oct1 H2O2-HelaGSE14283 72213345 72213373 28 0
Oct1 H2O2-HelaGSE14283 72214160 72214190 30 0
Oct1 H2O2-HelaGSE14283 72360030 72360057 27 0
Oct1 HelaGSE14283 71661023 71661082 59 0
Oct1 HelaGSE14283 71689315 71689345 30 0
Oct1 HelaGSE14283 71763145 71763184 39 0
Oct1 HelaGSE14283 71825205 71825233 28 0
Oct1 HelaGSE14283 71827824 71827873 49 0
Oct1 HelaGSE14283 71839731 71839796 65 0
Oct1 HelaGSE14283 71902498 71902569 71 0
Oct1 HelaGSE14283 71937513 71937556 43 0
Oct1 HelaGSE14283 71965064 71965139 75 0
Oct1 HelaGSE14283 72002648 72002692 44 0
Oct1 HelaGSE14283 72007598 72007649 51 0
Oct1 HelaGSE14283 72014131 72014161 30 0
Oct1 HelaGSE14283 72034937 72034964 27 0
Oct1 HelaGSE14283 72057732 72057806 74 0
Oct1 HelaGSE14283 72141671 72141703 32 0
Oct1 HelaGSE14283 72172186 72172218 32 0
Oct1 HelaGSE14283 72188322 72188406 84 0
Oct1 HelaGSE14283 72213330 72213374 44 0
Oct1 HelaGSE14283 72214151 72214190 39 0
Oct1 HelaGSE14283 72220980 72221010 30 0
Oct1 HelaGSE14283 72227061 72227134 73 0
Oct1 HelaGSE14283 72299853 72299889 36 0
Oct1 HelaGSE14283 72338196 72338241 45 0
Oct1 HelaGSE14283 72347415 72347448 33 0
Oct1 HelaGSE14283 72514129 72514213 84 0
Oct4 hESGSE17917 71700563 71700869 306 0
Oct4 hESGSE21916 71700500 71700912 412 0
RNAII Tamoxifen-MCF7GSE14664 72134380 72134474 94 0
RNAII Tamoxifen-MCF7GSE14664 72315036 72315128 92 0
TFAP2C MCF7GSE21234 72239011 72239423 412 0
p63 keratinocytesGSE17611 72238852 72239681 829 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
966 EST chr1 71579550 71585428 4782 mRNA NEGR1 chr1 71580646 72278635 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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