AutismKB 2.0

Annotation Detail for MTO1


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Basic Information Top
Gene Symbol:MTO1 ( - )
Gene Full Name: mitochondrial translation optimization 1 homolog (S. cerevisiae)
Band: 6q13
Quick LinksEntrez ID:25821; OMIM: NA; Uniprot ID:MTO1_HUMAN; ENSEMBL ID: ENSG00000135297; HGNC ID: 19261
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
471Phosphotyrosine.
488Phosphotyrosine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
34Phosphothreonine(MAPK)HMM predict
185Phosphotyrosine(EGFR)HMM predict
224Phosphothreonine(PKC)HMM predict
239Phosphothreonine(CDC2)HMM predict
260N-linkedHMM predict
269N-linkedHMM predict
345SulfotyrosineHMM predict
409PhosphotyrosineHMM predict
416Phosphothreonine(PKA)HMM predict
434N-linkedHMM predict
439Phosphotyrosine(Syk)HMM predict
439Phosphotyrosine(INSR)HMM predict
458Phosphoserine(PKG)HMM predict
511Phosphothreonine(PKC)HMM predict
564Phosphothreonine(PKC)HMM predict
565O-linkedHMM predict
664Phosphothreonine(PKC)HMM predict
694Phosphoserine(PKA)HMM predict
694Phosphoserine(PKG)HMM predict
697N-linkedHMM predict
700Phosphoserine(CK1)HMM predict
705Phosphotyrosine(Jak)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_012123
  • Location:chr6 74228208-74267538
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TAF HelaGSE8489 74228070 74228326 256 11
hScc1 CdLSGSE12603 74228070 74228283 213 32
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 74227591 74229190 1599 0
CTCF G2GSE9613 74228070 74228628 558 0
ETS1 JurkatGSE17954 74227953 74229007 1054 0
H3ac HepG2E 74228105 74228862 757 0
P300 T30-glioblastomaGSE21026 74227973 74228799 826 0
Rb QuiescentGSE19898 74228102 74228756 654 0
Rb SenescentGSE19898 74228050 74228653 603 0
Rb shRbSenescenceGSE19898 74228386 74228652 266 0
TAF k562GSE8489 74228070 74228862 792 0
TAFII hESGSE17917 74228106 74228550 444 0
p130 QuiescentGSE19898 74228341 74228604 263 0
p130 SenescentGSE19898 74228088 74228675 587 0
p130 shRbQuiescentGSE19898 74228182 74228905 723 0
p130 shRbSenescentGSE19898 74228117 74228700 583 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018