Annotation Detail for BACE2
Basic Information Top
| Gene Symbol: | BACE2 ( AEPLC,ALP56,ASP1,ASP21,BAE2,CEAP1,DRAP ) |
|---|---|
| Gene Full Name: | beta-site APP-cleaving enzyme 2 |
| Band: | 21q22.2-q22.3 |
| Quick Links | Entrez ID:25825; OMIM: 605668; Uniprot ID:BACE2_HUMAN; ENSEMBL ID: ENSG00000182240; HGNC ID: 934 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 170 | N-linked (GlcNAc...) (Potential). | |
| 366 | N-linked (GlcNAc...) (Potential). | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 170 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 366 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 46 | O-linked | HMM predict |
| 46 | Phosphothreonine(MAPK) | HMM predict |
| 51 | Phosphothreonine(CDK) | HMM predict |
| 51 | Phosphothreonine(MAPK) | HMM predict |
| 70 | Phosphoserine(CDC2) | HMM predict |
| 125 | Sulfotyrosine | HMM predict |
| 125 | Phosphotyrosine(INSR) | HMM predict |
| 137 | Phosphothreonine(PKC) | HMM predict |
| 138 | Phosphotyrosine(PKC) | HMM predict |
| 242 | O-linked | HMM predict |
| 327 | Phosphoserine(PKG) | HMM predict |
| 366 | N-linked | HMM predict |
| 399 | Phosphoserine(CDC2) | HMM predict |
| 511 | Phosphoserine(CK1) | HMM predict |
- RefSeq ID: NM_138992
- Location:chr21 41461597-41570392
- strand:+
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| ER | MCF7 | GSE19013 | 41442641 | 41443492 | 851 | 18531 |
| FOXA1 | MCF7 | GSE15244 | 41442130 | 41442912 | 782 | 19077 |
| FOXA1 | MCF7 | GSE15244 | 41443284 | 41443714 | 430 | 18099 |
| FOXA1 | MCF7 | GSE15244 | 41458829 | 41459625 | 796 | 2371 |
| RARA | MCF7 | GSE15244 | 41442199 | 41442912 | 713 | 19042 |
| RARA | MCF7 | GSE15244 | 41443284 | 41444083 | 799 | 17914 |
| RARA | MCF7 | GSE15244 | 41458829 | 41459625 | 796 | 2371 |
| RARG | MCF7 | GSE15244 | 41442199 | 41442912 | 713 | 19042 |
| RARG | MCF7 | GSE15244 | 41443284 | 41444083 | 799 | 17914 |
| RARG | MCF7 | GSE15244 | 41458829 | 41459812 | 983 | 2277 |
| p130 | Quiescent | GSE19898 | 41461465 | 41461711 | 246 | 10 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | CD4 | GSE12889 | 41577070 | 41577373 | 303 | 6829 |
| CTCF | CD4 | SISSRdata | 41577070 | 41577373 | 303 | 6829 |
| CTCF | G2 | GSE9613 | 41577071 | 41577406 | 335 | 6846 |
| hScc1 | Bcell | GSE12603 | 41576632 | 41577928 | 1296 | 6888 |
| hScc1 | CdLS | GSE12603 | 41576598 | 41577963 | 1365 | 6888 |
| hScc1 | G2 | GSE9613 | 41576970 | 41577627 | 657 | 6906 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CBP | Jurkat | GSE17954 | 41520155 | 41522922 | 2767 | 0 |
| Oct4 | hES | GSE17917 | 41493143 | 41493341 | 198 | 0 |
| P300 | T30-glioblastoma | GSE21026 | 41544049 | 41544999 | 950 | 0 |
| RARA | MCF7 | GSE15244 | 41542928 | 41543183 | 255 | 0 |
| Rb | Senescent | GSE19898 | 41462555 | 41462786 | 231 | 0 |
| TFAP2C | MCF7 | GSE21234 | 41511267 | 41511923 | 656 | 0 |
| hScc1 | Bcell | GSE12603 | 41461804 | 41462275 | 471 | 0 |
| hScc1 | Bcell | GSE12603 | 41542856 | 41543538 | 682 | 0 |
| hScc1 | CdLS | GSE12603 | 41461634 | 41462320 | 686 | 0 |
| p130 | Senescent | GSE19898 | 41461508 | 41461847 | 339 | 0 |
| p130 | shRbSenescent | GSE19898 | 41542431 | 41542612 | 181 | 0 |
Validated miRNA targets