AutismKB 2.0

Annotation Detail for PRKD2


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Basic Information Top
Gene Symbol:PRKD2 ( PKD2 )
Gene Full Name: protein kinase D2
Band: 19q13.2
Quick LinksEntrez ID:25865; OMIM: 607074; Uniprot ID:KPCD2_HUMAN; ENSEMBL ID: ENSG00000105287; HGNC ID: 17293
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
189Phosphoserine.
197Phosphoserine.
198Phosphoserine.
199Phosphothreonine.
200Phosphoserine.
203Phosphoserine.
206Phosphoserine.
212Phosphoserine (By similarity).
214Phosphoserine.
225Phosphoserine.
227Phosphothreonine.
236Phosphoserine.
237Phosphoserine.
238Phosphoserine.
338Phosphoserine.
353Phosphoserine.
355Phosphoserine.
362Phosphoserine.
374Phosphoserine.
375Phosphoserine.
396Phosphoserine.
518Phosphoserine.
706Phosphoserine.
710Phosphoserine; by autocatalysis (By
717Phosphotyrosine.
876Phosphoserine; by autocatalysis.
Location(AA) Modifications Resource
197Phosphoserine.Swiss-Prot 53.0
197PhosphoserinePhospho.ELM 6.0
198PhosphoserinePhospho.ELM 6.0
200Phosphoserine (By similarity).Swiss-Prot 53.0
212Phosphoserine (By similarity).Swiss-Prot 53.0
214Phosphoserine.Swiss-Prot 53.0
706PhosphoserinePhospho.ELM 6.0
710PhosphoserinePhospho.ELM 6.0
710Phosphoserine.Swiss-Prot 53.0
876Phosphoserine (PKD2)Phospho.ELM 6.0
876Phosphoserine (by autocatalysis).Swiss-Prot 53.0
Location(AA) Modification Resource
14Phosphoserine(CDC2)HMM predict
14Phosphoserine(ATM)HMM predict
14O-linkedHMM predict
19Phosphoserine(CDK)HMM predict
19Phosphoserine(IKK)HMM predict
19O-linkedHMM predict
19Phosphoserine(CDC2)HMM predict
172S-palmitoylHMM predict
197Phosphoserine(CK1)HMM predict
197Phosphoserine(PKG)HMM predict
197Phosphoserine(PKA)HMM predict
211Phosphothreonine(PKC)HMM predict
223Phosphoserine(CK1)HMM predict
225Phosphoserine(CK1)HMM predict
236Phosphoserine(CK2)HMM predict
236Phosphoserine(IKK)HMM predict
237Phosphoserine(CDK)HMM predict
237O-linkedHMM predict
237O-linkedHMM predict
239Phosphoserine(CK1)HMM predict
244Phosphoserine(CK1)HMM predict
347Phosphoserine(CK1)HMM predict
362PhosphoserineHMM predict
362Phosphoserine(CK2)HMM predict
378Phosphotyrosine(Jak)HMM predict
378Phosphotyrosine(INSR)HMM predict
391Phosphothreonine(PKC)HMM predict
392Phosphothreonine(PKC)HMM predict
398Phosphothreonine(PKC)HMM predict
412Phosphothreonine(PKC)HMM predict
431N-linkedHMM predict
432N-linkedHMM predict
435N-linkedHMM predict
454N-linkedHMM predict
456O-linkedHMM predict
473N-linkedHMM predict
518O-linkedHMM predict
529Phosphoserine(PKB)HMM predict
573Phosphothreonine(PKA)HMM predict
619Phosphothreonine(CDC2)HMM predict
710Phosphoserine(PKA)HMM predict
773C-linkedHMM predict
797Phosphoserine(CAMK2)HMM predict
801Phosphoserine(IKK)HMM predict
849Phosphoserine(IKK)HMM predict
861S-farnesylHMM predict
875IsoleucineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_016457
  • Location:chr19 51869413-51911505
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me3 colorectalcancer 51911678 51912414 736 541
H3ac HepG2E 51911678 51912052 374 360
VDR GM10861-stimGSE22484 51908015 51915315 7300 160
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 51861670 51861710 40 7724
Oct1 HelaGSE14283 51861670 51861710 40 7724
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 51899634 51899856 222 0
CTCF CD4SISSRdata 51899634 51899856 222 0
CTCF HelaGSE12889 51899616 51899958 342 0
CTCF G2GSE9613 51899470 51900138 668 0
Fos K562GSE19551 51869888 51870353 465 0
H3ac HepG2E 51909587 51911038 1451 0
Rb SenescentGSE19898 51892849 51893090 241 0
Stat6 IL-4-hr4GSE17850 51891114 51891652 538 0
VDR GM10861-stimGSE22484 51899073 51900685 1612 0
hScc1 BcellGSE12603 51872189 51872319 130 0
hScc1 BcellGSE12603 51872853 51873533 680 0
hScc1 BcellGSE12603 51881074 51881293 219 0
hScc1 BcellGSE12603 51887446 51887706 260 0
hScc1 BcellGSE12603 51899535 51900293 758 0
hScc1 BcellGSE12603 51910971 51911318 347 0
hScc1 CdLSGSE12603 51899316 51900176 860 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-17 hsa-mir-17 13 20215348
hsa-miR-17 hsa-mir-17 13 19821056
hsa-miR-17 hsa-mir-17 13 20215348
hsa-miR-17 hsa-mir-17 13 19821056
hsa-miR-17* hsa-mir-17 13 20215348
hsa-miR-17* hsa-mir-17 13 19821056
hsa-miR-17* hsa-mir-17 13 20215348
hsa-miR-17* hsa-mir-17 13 19821056
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
13386 EST chr19 51869415 51873547 551 mRNA PRKD2 chr19 51869412 51911506Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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