AutismKB 2.0

Annotation Detail for ASPM


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Basic Information Top
Gene Symbol:ASPM ( ASP,Calmbp1,DKFZp686N06184,FLJ10517,FLJ10549,FLJ43117,MCPH5 )
Gene Full Name: asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
Band: 1q31.3
Quick LinksEntrez ID:259266; OMIM: 605481; Uniprot ID:ASPM_HUMAN; ENSEMBL ID: ENSG00000066279; HGNC ID: 19048
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
14Phosphoserine.
35Phosphoserine.
170Phosphoserine.
178Phosphothreonine.
211Phosphoserine.
222Phosphoserine.
225Phosphoserine.
246Phosphothreonine.
249Phosphoserine.
263Phosphoserine.
267Phosphoserine.
270Phosphoserine.
277Phosphothreonine.
280Phosphoserine.
283Phosphoserine.
348Phosphoserine.
367Phosphoserine.
370Phosphoserine.
392Phosphoserine.
425Phosphoserine.
463Phosphoserine.
563Phosphothreonine.
565Phosphoserine.
566Phosphoserine.
570Phosphoserine.
577Phosphoserine.
605Phosphoserine.
647Phosphothreonine.
1103Phosphoserine.
1105Phosphoserine.
2429Phosphoserine.
3186Phosphoserine.
3435Phosphothreonine.
Location(AA) Modifications Resource
14Phosphoserine.Swiss-Prot 53.0
14PhosphoserinePhospho.ELM 6.0
35Phosphoserine.Swiss-Prot 53.0
35PhosphoserinePhospho.ELM 6.0
222Phosphoserine.Swiss-Prot 53.0
222PhosphoserinePhospho.ELM 6.0
225Phosphoserine.Swiss-Prot 53.0
225PhosphoserinePhospho.ELM 6.0
263PhosphoserinePhospho.ELM 6.0
263Phosphoserine.Swiss-Prot 53.0
267PhosphoserinePhospho.ELM 6.0
267Phosphoserine.Swiss-Prot 53.0
270PhosphoserinePhospho.ELM 6.0
270Phosphoserine.Swiss-Prot 53.0
280PhosphoserinePhospho.ELM 6.0
280Phosphoserine.Swiss-Prot 53.0
283PhosphoserinePhospho.ELM 6.0
283Phosphoserine.Swiss-Prot 53.0
348Phosphoserine.Swiss-Prot 53.0
348PhosphoserinePhospho.ELM 6.0
367PhosphoserinePhospho.ELM 6.0
367Phosphoserine.Swiss-Prot 53.0
370PhosphoserinePhospho.ELM 6.0
370Phosphoserine.Swiss-Prot 53.0
392PhosphoserinePhospho.ELM 6.0
392Phosphoserine.Swiss-Prot 53.0
425Phosphoserine.Swiss-Prot 53.0
425PhosphoserinePhospho.ELM 6.0
463PhosphoserinePhospho.ELM 6.0
463Phosphoserine.Swiss-Prot 53.0
563Phosphothreonine.Swiss-Prot 53.0
563PhosphothreoninePhospho.ELM 6.0
605PhosphoserinePhospho.ELM 6.0
605Phosphoserine.Swiss-Prot 53.0
647PhosphothreoninePhospho.ELM 6.0
647Phosphothreonine.Swiss-Prot 53.0
1103PhosphoserinePhospho.ELM 6.0
1103Phosphoserine.Swiss-Prot 53.0
2429PhosphoserinePhospho.ELM 6.0
2429Phosphoserine.Swiss-Prot 53.0
3435Phosphothreonine.Swiss-Prot 53.0
3435PhosphothreoninePhospho.ELM 6.0
Location(AA) Modification Resource
16Phosphothreonine(PKC)HMM predict
34O-linkedHMM predict
35Phosphoserine(ATM)HMM predict
35Phosphoserine(MAPK)HMM predict
109N-linkedHMM predict
160Phosphoserine(PKG)HMM predict
170Phosphoserine(PKG)HMM predict
176N-linkedHMM predict
182Phosphoserine(ATM)HMM predict
190Phosphoserine(CDK)HMM predict
222Phosphoserine(CDC2)HMM predict
222Phosphoserine(CDK)HMM predict
245Phosphothreonine(PKA)HMM predict
245Phosphothreonine(PKC)HMM predict
246Phosphothreonine(PKC)HMM predict
247Phosphotyrosine(SRC)HMM predict
265N-linkedHMM predict
301N-linkedHMM predict
307N-linkedHMM predict
348Phosphoserine(ATM)HMM predict
362Phosphotyrosine(Syk)HMM predict
367Phosphoserine(MAPK)HMM predict
384Phosphoserine(CK1)HMM predict
386Phosphoserine(ATM)HMM predict
403Phosphotyrosine(INSR)HMM predict
446Phosphoserine(CDC2)HMM predict
480Phosphoserine(CK1)HMM predict
498Phosphothreonine(PKC)HMM predict
508N-linkedHMM predict
513N-linkedHMM predict
558Phosphotyrosine(INSR)HMM predict
563Phosphothreonine(MAPK)HMM predict
563Phosphothreonine(CDK)HMM predict
563O-linkedHMM predict
565Phosphoserine(MAPK)HMM predict
566O-linkedHMM predict
566O-linkedHMM predict
566O-linkedHMM predict
567O-linkedHMM predict
567O-linkedHMM predict
568O-linkedHMM predict
605Phosphoserine(CDC2)HMM predict
612O-linkedHMM predict
619N-linkedHMM predict
647Phosphothreonine(CDC2)HMM predict
1024Phosphoserine(ATM)HMM predict
1044Phosphothreonine(PKC)HMM predict
1109Phosphotyrosine(INSR)HMM predict
1133N-linkedHMM predict
1172O-linkedHMM predict
1180N-linkedHMM predict
1183Phosphoserine(CK2)HMM predict
1185Phosphoserine(ATM)HMM predict
1188Phosphoserine(IKK)HMM predict
1235N-linkedHMM predict
1241N-linkedHMM predict
1362Phosphoserine(PKA)HMM predict
1417Phosphotyrosine(Syk)HMM predict
1513Phosphoserine(PKA)HMM predict
1513Phosphoserine(PKG)HMM predict
1725Phosphotyrosine(INSR)HMM predict
1725Phosphotyrosine(SRC)HMM predict
1771Phosphotyrosine(Syk)HMM predict
2059Phosphothreonine(PKC)HMM predict
2065Phosphothreonine(PKC)HMM predict
2185Phosphothreonine(PKC)HMM predict
2275Phosphothreonine(PKA)HMM predict
2400Phosphothreonine(PKC)HMM predict
2730Phosphothreonine(PKC)HMM predict
2771N-linkedHMM predict
2777S-palmitoylHMM predict
2784Phosphotyrosine(SRC)HMM predict
2784Phosphotyrosine(Syk)HMM predict
2806Phosphoserine(ATM)HMM predict
2813Phosphoserine(ATM)HMM predict
2830Phosphothreonine(PKA)HMM predict
2835Phosphothreonine(PKC)HMM predict
2898Phosphoserine(CDK)HMM predict
2934N-linkedHMM predict
3083Phosphothreonine(PKA)HMM predict
3186Phosphoserine(CAMK2)HMM predict
3262Phosphothreonine(PKC)HMM predict
3414Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_018136
  • Location:chr1 195320076-195382189
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
E2F4 SGSE7516 195382361 195382823 462 403
Fos K562GSE19551 195382009 195383029 1020 330
H3K4me3 colorectalcancer 195382361 195382753 392 368
H3ac HepG2E 195382532 195382896 364 525
LIN54 SGSE7516 195382361 195382753 392 368
LIN9 SGSE7516 195382361 195382896 535 439
PHF8 293TGSE20725 195381787 195382861 1074 135
TAF k562GSE8489 195382361 195383064 703 523
p130 QuiescentGSE19898 195382015 195382856 841 246
p130 SenescentGSE19898 195381627 195383041 1414 145
p130 shRbQuiescentGSE19898 195381919 195382958 1039 249
p130 shRbSenescentGSE19898 195381726 195382954 1228 151
p130 SGSE7516 195382361 195382896 535 439
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
E2F4 G0GSE7516 195381802 195382049 247 0
H3K4me3 colorectalcancer 195381163 195381984 821 0
H3ac HepG2E 195380907 195382049 1142 0
LIN54 G0GSE7516 195381802 195382049 247 0
LIN9 G0GSE7516 195381562 195382049 487 0
LIN9 SGSE7516 195381725 195382049 324 0
Oct1 HelaGSE14283 195333567 195333658 91 0
TAF k562GSE8489 195380795 195382049 1254 0
hScc1 BcellGSE12603 195381725 195382049 324 0
p130 G0GSE7516 195381650 195382049 399 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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