AutismKB 2.0

Annotation Detail for SIN3A


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Basic Information Top
Gene Symbol:SIN3A ( DKFZp434K2235,FLJ90319,KIAA0700 )
Gene Full Name: SIN3 homolog A, transcription regulator (yeast)
Band: 15q24.2
Quick LinksEntrez ID:25942; OMIM: 607776; Uniprot ID:SIN3A_HUMAN; ENSEMBL ID: ENSG00000169375; HGNC ID: 19353
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
10Phosphoserine.
277Phosphoserine.
289Phosphoserine.
469N6-acetyllysine.
723N6-acetyllysine.
727N6-acetyllysine.
832Phosphoserine.
860Phosphoserine.
934N6-acetyllysine.
940Phosphoserine.
1108Phosphoserine.
1112Phosphoserine.
Location(AA) Modifications Resource
832Phosphoserine.Swiss-Prot 53.0
832PhosphoserinePhospho.ELM 6.0
860Phosphoserine.Swiss-Prot 53.0
860PhosphoserinePhospho.ELM 6.0
1112Phosphoserine.Swiss-Prot 53.0
1112PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
13Phosphotyrosine(Abl)HMM predict
41Phosphotyrosine(SRC)HMM predict
70O-linkedHMM predict
71O-linkedHMM predict
144Phosphotyrosine(EGFR)HMM predict
144Phosphotyrosine(Syk)HMM predict
158Phosphoserine(IKK)HMM predict
201N-linkedHMM predict
228Phosphoserine(ATM)HMM predict
234Phosphoserine(IKK)HMM predict
251Phosphoserine(IKK)HMM predict
251Phosphoserine(PKG)HMM predict
263Phosphoserine(ATM)HMM predict
263O-linkedHMM predict
274Phosphoserine(CDK)HMM predict
274O-linkedHMM predict
274Phosphoserine(CDC2)HMM predict
277Phosphoserine(MAPK)HMM predict
277O-linkedHMM predict
284Phosphothreonine(MAPK)HMM predict
287O-linkedHMM predict
289O-linkedHMM predict
325Phosphotyrosine(EGFR)HMM predict
348N-linkedHMM predict
359Phosphotyrosine(Syk)HMM predict
359Phosphotyrosine(Abl)HMM predict
399Phosphoserine(CK2)HMM predict
407Phosphothreonine(PKC)HMM predict
421Phosphoserine(IKK)HMM predict
432Phosphothreonine(PKA)HMM predict
480Phosphotyrosine(Syk)HMM predict
582N-linkedHMM predict
599Phosphoserine(CDC2)HMM predict
605Phosphotyrosine(EGFR)HMM predict
610Phosphotyrosine(INSR)HMM predict
610Phosphotyrosine(SRC)HMM predict
644Phosphoserine(PKG)HMM predict
644Phosphoserine(CK1)HMM predict
739N-linkedHMM predict
765Phosphothreonine(CK2)HMM predict
802Phosphothreonine(PKA)HMM predict
832Phosphoserine(CK2)HMM predict
860Phosphoserine(ATM)HMM predict
860Phosphoserine(CDC2)HMM predict
938Phosphoserine(CK2)HMM predict
940Phosphoserine(CDC2)HMM predict
958Phosphotyrosine(Syk)HMM predict
959Phosphotyrosine(EGFR)HMM predict
977Phosphoserine(ATM)HMM predict
979Phosphotyrosine(Syk)HMM predict
1044Phosphoserine(CK1)HMM predict
1084Phosphothreonine(CK2)HMM predict
1112Phosphoserine(MAPK)HMM predict
1185Phosphotyrosine(INSR)HMM predict
1230Phosphothreonine(PKC)HMM predict
1247O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_015477
  • Location:chr15 73450329-73530978
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 73532412 73532883 471 1669
CTCF G2GSE9613 73533649 73534109 460 2901
CTCF G2GSE9613 73534514 73534948 434 3753
FOXA1 MCF7GSE15244 73531274 73533511 2237 1414
FOXA1 eGFPGSE10845 73531274 73533511 2237 1414
H3K4me3 colorectalcancer 73531973 73533069 1096 1543
H3K4me3 colorectalcancer 73534635 73535016 381 3847
H3ac HepG2E 73531865 73533362 1497 1635
H3ac HepG2E 73535549 73536719 1170 5156
Oct1 HelaGSE14283 73537872 73537910 38 6913
Rb SenescentGSE19898 73530930 73532140 1210 557
TAF HelaGSE8489 73531834 73533321 1487 1599
TFAP2C MCF7GSE21234 73532456 73533845 1389 2172
hScc1 BcellGSE12603 73532345 73532994 649 1691
hScc1 BcellGSE12603 73533786 73535794 2008 3812
p130 QuiescentGSE19898 73533185 73533590 405 2409
p130 SenescentGSE19898 73531020 73531679 659 371
p130 SenescentGSE19898 73532974 73533745 771 2381
p130 SenescentGSE19898 73535331 73535877 546 4626
p130 shRbQuiescentGSE19898 73535023 73535853 830 4460
p130 shRbSenescentGSE19898 73530953 73531861 908 429
p130 shRbSenescentGSE19898 73533085 73533822 737 2475
p130 shRbSenescentGSE19898 73535189 73535769 580 4501
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 73449307 73449336 29 1008
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 73530014 73530838 824 0
Fos K562GSE19551 73523409 73523716 307 0
H3ac HepG2E 73451123 73451525 402 0
H3ac HepG2E 73526726 73527148 422 0
H3ac HepG2E 73528637 73529128 491 0
H3ac HepG2E 73529488 73530081 593 0
NRSF mAbJurkat 73479256 73479696 440 0
Oct1 H2O2-HelaGSE14283 73480538 73480569 31 0
Oct1 HelaGSE14283 73479666 73479701 35 0
Oct1 HelaGSE14283 73480540 73480569 29 0
Oct1 HelaGSE14283 73485802 73485835 33 0
Oct1 HelaGSE14283 73488933 73488974 41 0
Oct1 HelaGSE14283 73504514 73504549 35 0
TAF HelaGSE8489 73478964 73479696 732 0
TFAP2C MCF7GSE21234 73529658 73530479 821 0
hScc1 BcellGSE12603 73529786 73531032 1246 0
p130 shRbSenescentGSE19898 73509547 73509719 172 0
p63 keratinocytesGSE17611 73450592 73451591 999 0
p63 keratinocytesGSE17611 73522427 73523316 889 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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