Annotation Detail for TBC1D10B

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Basic Information Top

Gene Symbol:	TBC1D10B ( DKFZp434P1750 )
Gene Full Name:	TBC1 domain family, member 10B
Band:	16p11.2
Quick Links	Entrez ID:26000; OMIM: 613620; Uniprot ID:TB10B_HUMAN; ENSEMBL ID: ENSG00000169221; HGNC ID: 24510
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:6 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:0 results

Location(AA)	Modification
658	Phosphoserine.
661	Phosphoserine.
678	Phosphoserine.
687	Phosphoserine.
707	Phosphoserine.
709	Phosphothreonine.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_015527
Location:chr16 30275923-30288401
strand:-

Upstream the gene:13 results
Downstream the gene:1 results
Inside the gene:5 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	30289905	30290131	226	1617
CTCF	CD4	SISSRdata	30289905	30290131	226	1617
H3ac	HepG2	E	30289993	30291541	1548	2366
Rb	Growing	GSE19898	30289207	30289412	205	908
Rb	Growing	GSE19898	30289500	30289663	163	1180
Rb	Quiescent	GSE19898	30289277	30289447	170	961
Rb	Quiescent	GSE19898	30289570	30289757	187	1262
Rb	Senescent	GSE19898	30289113	30289788	675	1049
hScc1	Bcell	GSE12603	30290071	30290456	385	1862
p130	Quiescent	GSE19898	30289299	30289498	199	997
p130	Senescent	GSE19898	30289292	30289893	601	1191
p130	shRbSenescent	GSE19898	30289262	30289448	186	954
p130	shRbSenescent	GSE19898	30289524	30289668	144	1195

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
H3ac	HepG2	E	30274177	30276120	1943	775

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
H3K4me3	colorectal	cancer	30286160	30287037	877	0
H3ac	HepG2	E	30286160	30288110	1950	0
Oct1	Hela	GSE14283	30280535	30280571	36	0
TFAP2C	MCF7	GSE21234	30278571	30279180	609	0
TFAP2C	MCF7	GSE21234	30285186	30285814	628	0

Validated miRNA targets

Cis-Nats regulation

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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