AutismKB 2.0

Annotation Detail for SIPA1L1


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Basic Information Top
Gene Symbol:SIPA1L1 ( DKFZp686G1344,E6TP1,KIAA0440 )
Gene Full Name: signal-induced proliferation-associated 1 like 1
Band: 14q24.1
Quick LinksEntrez ID:26037; OMIM: NA; Uniprot ID:SI1L1_HUMAN; ENSEMBL ID: ENSG00000197555; HGNC ID: 20284
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
161Phosphoserine.
162Phosphoserine.
288Phosphoserine.
1255Phosphoserine.
1257Phosphoserine.
1270Phosphoserine.
1433Phosphoserine.
1528Phosphoserine.
1549Phosphoserine.
1551Phosphothreonine.
1568Phosphoserine (By similarity).
1583Phosphothreonine.
1585Phosphoserine.
1647Phosphoserine.
1650Phosphoserine.
1727Phosphotyrosine.
1730Phosphoserine.
Location(AA) Modifications Resource
1257Phosphoserine.Swiss-Prot 53.0
1257PhosphoserinePhospho.ELM 6.0
1270Phosphoserine.Swiss-Prot 53.0
1270PhosphoserinePhospho.ELM 6.0
1433Phosphoserine.Swiss-Prot 53.0
1433PhosphoserinePhospho.ELM 6.0
1528PhosphoserinePhospho.ELM 6.0
1528Phosphoserine.Swiss-Prot 53.0
1549PhosphoserinePhospho.ELM 6.0
1549Phosphoserine.Swiss-Prot 53.0
1568Phosphoserine (By similarity).Swiss-Prot 53.0
1585PhosphoserinePhospho.ELM 6.0
1585Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
9Phosphothreonine(PKC)HMM predict
26Phosphothreonine(CDC2)HMM predict
41Phosphoserine(IKK)HMM predict
43N-linkedHMM predict
45Phosphoserine(IKK)HMM predict
59O-linkedHMM predict
67O-linkedHMM predict
96Phosphoserine(CK1)HMM predict
97Phosphoserine(CK1)HMM predict
97Phosphoserine(ATM)HMM predict
108O-linkedHMM predict
110Phosphoserine(CK1)HMM predict
110Phosphoserine(CK2)HMM predict
111Phosphoserine(CK1)HMM predict
114Phosphoserine(CDC2)HMM predict
114Phosphoserine(IKK)HMM predict
117Phosphoserine(ATM)HMM predict
117Phosphoserine(IKK)HMM predict
121Phosphoserine(IKK)HMM predict
123Phosphoserine(IKK)HMM predict
141N-linkedHMM predict
162Phosphoserine(CDC2)HMM predict
162Phosphoserine(CDK)HMM predict
176Phosphoserine(CK1)HMM predict
217Phosphothreonine(PKC)HMM predict
239Phosphothreonine(MAPK)HMM predict
239Phosphothreonine(CDK)HMM predict
267Phosphoserine(ATM)HMM predict
288Phosphoserine(IKK)HMM predict
290Phosphothreonine(PKC)HMM predict
311Phosphoserine(CK2)HMM predict
316N-linkedHMM predict
318Phosphoserine(CK1)HMM predict
358N-linkedHMM predict
359Phosphothreonine(PKA)HMM predict
364O-linkedHMM predict
370O-linkedHMM predict
381Phosphoserine(CAMK2)HMM predict
381Phosphoserine(IKK)HMM predict
384Phosphoserine(CDC2)HMM predict
394Phosphoserine(CK1)HMM predict
430Phosphoserine(PKG)HMM predict
430Phosphoserine(CAMK2)HMM predict
430Phosphoserine(PKB)HMM predict
434Phosphoserine(IKK)HMM predict
438Phosphoserine(IKK)HMM predict
449O-linkedHMM predict
450O-linkedHMM predict
529N-linkedHMM predict
534N-linkedHMM predict
546Phosphothreonine(PKC)HMM predict
563O-linkedHMM predict
623Phosphoserine(CK2)HMM predict
629Phosphotyrosine(INSR)HMM predict
629Phosphotyrosine(Syk)HMM predict
668O-linkedHMM predict
677Phosphotyrosine(Syk)HMM predict
693Phosphothreonine(CDC2)HMM predict
724Phosphoserine(CDC2)HMM predict
820N-linkedHMM predict
823N-linkedHMM predict
898N-linkedHMM predict
1004Phosphothreonine(PKC)HMM predict
1032Phosphothreonine(CDC2)HMM predict
1032Phosphothreonine(MAPK)HMM predict
1036Phosphoserine(PKA)HMM predict
1041Phosphotyrosine(Abl)HMM predict
1071N-linkedHMM predict
1078Phosphoserine(CDC2)HMM predict
1078Phosphoserine(ATM)HMM predict
1127Phosphoserine(PKG)HMM predict
1127Phosphoserine(MAPK)HMM predict
1133Phosphotyrosine(EGFR)HMM predict
1133Phosphotyrosine(INSR)HMM predict
1133Phosphotyrosine(Jak)HMM predict
1149Phosphoserine(CDC2)HMM predict
1152N-linkedHMM predict
1154Phosphoserine(CK1)HMM predict
1154Phosphoserine(CK2)HMM predict
1157Phosphoserine(CK1)HMM predict
1161Phosphoserine(IKK)HMM predict
1170Phosphoserine(PKB)HMM predict
1181Phosphoserine(CDC2)HMM predict
1210Phosphoserine(CK2)HMM predict
1210Phosphoserine(IKK)HMM predict
1235Phosphotyrosine(INSR)HMM predict
1235Phosphotyrosine(SRC)HMM predict
1235Phosphotyrosine(Abl)HMM predict
1235Phosphotyrosine(Syk)HMM predict
1235PhosphotyrosineHMM predict
1255Phosphoserine(CDC2)HMM predict
1282Phosphoserine(CK2)HMM predict
1287O-linkedHMM predict
1287Phosphoserine(IKK)HMM predict
1289O-linkedHMM predict
1293N-linkedHMM predict
1299Phosphoserine(CK1)HMM predict
1330O-linkedHMM predict
1336O-linkedHMM predict
1339O-linkedHMM predict
1349O-linkedHMM predict
1393Phosphoserine(CK1)HMM predict
1398Phosphoserine(CK1)HMM predict
1400Phosphoserine(IKK)HMM predict
1404Phosphoserine(IKK)HMM predict
1405Phosphothreonine(MAPK)HMM predict
1405Phosphothreonine(CDK)HMM predict
1411N-linkedHMM predict
1417N-linkedHMM predict
1431Phosphoserine(PKG)HMM predict
1433Phosphoserine(MAPK)HMM predict
1443Phosphoserine(CDC2)HMM predict
1454Phosphoserine(IKK)HMM predict
1461O-linkedHMM predict
1461Phosphoserine(CK1)HMM predict
1466Phosphoserine(CK1)HMM predict
1468Phosphoserine(CK1)HMM predict
1528Phosphoserine(CDC2)HMM predict
1532O-linkedHMM predict
1532Phosphothreonine(PKC)HMM predict
1551Phosphothreonine(CDC2)HMM predict
1568Phosphoserine(CDC2)HMM predict
1572O-linkedHMM predict
1573Phosphothreonine(MAPK)HMM predict
1573Phosphothreonine(CDK)HMM predict
1585Phosphoserine(CK1)HMM predict
1590Phosphotyrosine(Syk)HMM predict
1592Phosphoserine(ATM)HMM predict
1619Phosphotyrosine(EGFR)HMM predict
1621O-linkedHMM predict
1647Phosphoserine(CK2)HMM predict
1649Phosphoserine(IKK)HMM predict
1650Phosphoserine(CK1)HMM predict
1711Phosphoserine(CK2)HMM predict
1729Phosphoserine(CDK)HMM predict
1733O-linkedHMM predict
1733Phosphoserine(CK1)HMM predict
1734Phosphoserine(CDK)HMM predict
1736Phosphothreonine(PKC)HMM predict
1783Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_015556
  • Location:chr14 71065794-71275870
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 71063942 71063970 28 1839
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 71289628 71289893 265 13890
CTCF CD4SISSRdata 71289628 71289893 265 13890
CTCF HelaGSE12889 71289621 71289930 309 13905
Fos K562GSE19551 71287554 71288099 545 11956
Nanog hESGSE18292 71291888 71292326 438 16237
RARA MCF7GSE15244 71288926 71290083 1157 13634
RARA MCF7GSE15244 71290645 71291235 590 15070
RARG MCF7GSE15244 71290664 71291235 571 15079
Rb GrowingGSE19898 71289485 71289856 371 13800
Rb QuiescentGSE19898 71289598 71289894 296 13876
Rb SenescentGSE19898 71289661 71289843 182 13882
Rb shRbSenescenceGSE19898 71289631 71289874 243 13882
TFAP2C MCF7GSE21234 71290444 71291501 1057 15102
hScc1 BcellGSE12603 71289252 71290083 831 13797
hScc1 CdLSGSE12603 71288847 71290083 1236 13595
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 71163100 71163649 549 0
CTCF G2GSE9613 71245870 71246051 181 0
ER E2-MCF7GSE14664 71089242 71089277 35 0
ER Fulvestrant-MCF7GSE14664 71089241 71089277 36 0
FoxA1 MCF7MACSdata 71238525 71238751 226 0
GABP HelaGSE8489 71183244 71183833 589 0
Myc hESGSE17917 71220876 71221230 354 0
Nanog hESGSE18292 71211739 71212222 483 0
Nanog hESGSE18292 71217737 71218282 545 0
Nanog hESGSE18292 71257465 71257768 303 0
Oct1 H2O2-HelaGSE14283 71089241 71089275 34 0
Oct1 H2O2-HelaGSE14283 71106370 71106396 26 0
Oct1 H2O2-HelaGSE14283 71136027 71136053 26 0
Oct1 H2O2-HelaGSE14283 71261825 71261856 31 0
Oct1 HelaGSE14283 71089238 71089277 39 0
Oct1 HelaGSE14283 71104827 71104883 56 0
Oct1 HelaGSE14283 71106367 71106403 36 0
Oct1 HelaGSE14283 71119317 71119346 29 0
Oct1 HelaGSE14283 71136022 71136063 41 0
Oct1 HelaGSE14283 71173344 71173372 28 0
P300 T0-glioblastomaGSE21026 71163437 71163893 456 0
P300 T30-glioblastomaGSE21026 71238286 71239092 806 0
PAX3-FKHR Rh4GSE19063 71247654 71249250 1596 0
RARA MCF7GSE15244 71093651 71093894 243 0
RARA MCF7GSE15244 71182933 71184444 1511 0
RARG MCF7GSE15244 71182933 71184444 1511 0
RARG MCF7GSE15244 71208681 71209185 504 0
Rb GrowingGSE19898 71240099 71240233 134 0
Sox2 hESGSE18292 71211936 71212214 278 0
Sox2 hESGSE18292 71257564 71257782 218 0
TFAP2C MCF7GSE21234 71157692 71158071 379 0
p130 shRbQuiescentGSE19898 71241805 71242242 437 0
p63 keratinocytesGSE17611 71133924 71134741 817 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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