Annotation Detail for LRRTM2

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Basic Information Top

Gene Symbol:	LRRTM2 ( FLJ76283,FLJ99831 )
Gene Full Name:	leucine rich repeat transmembrane neuronal 2
Band:	5q31.2
Quick Links	Entrez ID:26045; OMIM: 610868; Uniprot ID:LRRT2_HUMAN; ENSEMBL ID: ENSG00000146006; HGNC ID: 19409
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:4 results
Experimental PTM Sites from dbPTM:4 results
Predicted PTM Sites by profile HMM from dbPTM:13 results

Location(AA)	Modification
57	N-linked (GlcNAc...) (Potential).
126	N-linked (GlcNAc...) (Potential).
243	N-linked (GlcNAc...) (Potential).
362	N-linked (GlcNAc...) (Potential).

Location(AA)	Modifications	Resource
57	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
126	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
243	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
362	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0

Location(AA)	Modification	Resource
57	N-linked	HMM predict
126	N-linked	HMM predict
362	N-linked	HMM predict
368	O-linked	HMM predict
386	Phosphoserine(PKG)	HMM predict
386	Phosphoserine	HMM predict
447	S-palmitoyl	HMM predict
448	S-palmitoyl	HMM predict
477	N-linked	HMM predict
484	Phosphotyrosine(Syk)	HMM predict
487	Phosphotyrosine(Syk)	HMM predict
487	Sulfotyrosine	HMM predict
511	Tyrosine	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_015564
Location:chr5 138232977-138238907
strand:-

Upstream the gene:0 results
Downstream the gene:0 results
Inside the gene:2 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	138235271	138235376	105	0
CTCF	CD4	SISSRdata	138235271	138235376	105	0

Validated miRNA targets

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
21525	mRNA	CTNNA1	chr5	138117005	138298621	5931	mRNA	LRRTM2	chr5	138232977	138238908	Non-exonic Bidirectional (NOB) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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