AutismKB 2.0

Annotation Detail for HERC4


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Basic Information Top
Gene Symbol:HERC4 ( DKFZp564G092,KIAA1593 )
Gene Full Name: hect domain and RLD 4
Band: 10q21.3
Quick LinksEntrez ID:26091; OMIM: 609248; Uniprot ID:HERC4_HUMAN; ENSEMBL ID: ENSG00000148634; HGNC ID: 24521
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
830Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
179Phosphothreonine(PKA)HMM predict
277N-linkedHMM predict
306Phosphothreonine(PKC)HMM predict
306Phosphothreonine(PKA)HMM predict
337Phosphoserine(CDC2)HMM predict
378Phosphotyrosine(INSR)HMM predict
394N-linkedHMM predict
456Phosphoserine(PKA)HMM predict
479Phosphoserine(ATM)HMM predict
521N-linkedHMM predict
588Phosphoserine(CDK)HMM predict
807Phosphotyrosine(EGFR)HMM predict
808N-linkedHMM predict
863N-linkedHMM predict
906N-linkedHMM predict
958Phosphotyrosine(INSR)HMM predict
1018Phosphotyrosine(INSR)HMM predict
1018Phosphotyrosine(Syk)HMM predict
1039Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_015601
  • Location:chr10 69352252-69505018
  • strand:-
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER Fulvestrant-MCF7GSE14664 69394792 69394867 75 0
H3K4me2 HCT116GSE10453 69503747 69504384 637 0
H3K4me3 colorectalcancer 69503560 69504420 860 0
H3ac HepG2E 69502835 69504522 1687 0
NFkBII GM12892GSE19485 69503843 69505968 2125 0
Nanog hESGSE18292 69405514 69406122 608 0
Oct1 HelaGSE14283 69492888 69492952 64 0
PHF8 HeLaGSE20725 69504063 69505443 1380 0
Pol2 GM12878GSE19551 69504263 69505195 932 0
TAF HelaGSE8489 69503349 69504492 1143 0
TAF k562GSE8489 69385568 69385705 137 0
TAF k562GSE8489 69503277 69504492 1215 0
hScc1 BcellGSE12603 69504190 69504947 757 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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