AutismKB 2.0

Annotation Detail for INTS1


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Basic Information Top
Gene Symbol:INTS1 ( DKFZp586J0619,FLJ46624,INT1,KIAA1440,NET28 )
Gene Full Name: integrator complex subunit 1
Band: 7p22.3
Quick LinksEntrez ID:26173; OMIM: 611345; Uniprot ID:INT1_HUMAN; ENSEMBL ID: ENSG00000164880; HGNC ID: 24555
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
47N6-acetyllysine.
83Phosphothreonine.
1326Phosphoserine.
1327Phosphoserine.
1395Phosphoserine.
Location(AA) Modifications Resource
83PhosphothreoninePhospho.ELM 6.0
104PhosphoserinePhospho.ELM 6.0
1326Phosphoserine (By similarity).Swiss-Prot 53.0
1327Phosphoserine (By similarity).Swiss-Prot 53.0
1327PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
7Phosphothreonine(PKC)HMM predict
8Phosphothreonine(PKC)HMM predict
13Phosphoserine(PKA)HMM predict
19O-linkedHMM predict
37N-linkedHMM predict
67O-linkedHMM predict
67O-linkedHMM predict
69O-linkedHMM predict
81O-linkedHMM predict
83PhosphothreonineHMM predict
83Phosphothreonine(CDK)HMM predict
104Phosphoserine(CDC2)HMM predict
284Phosphoserine(ATM)HMM predict
295Phosphoserine(ATM)HMM predict
295Phosphoserine(CK1)HMM predict
295Phosphoserine(IKK)HMM predict
324Phosphoserine(CK1)HMM predict
324Phosphoserine(CK2)HMM predict
324Phosphoserine(PKG)HMM predict
360Phosphotyrosine(Syk)HMM predict
491Phosphotyrosine(EGFR)HMM predict
528Phosphotyrosine(INSR)HMM predict
528Phosphotyrosine(SRC)HMM predict
528PhosphotyrosineHMM predict
625SulfotyrosineHMM predict
762Phosphothreonine(PKC)HMM predict
774N-linkedHMM predict
775SulfotyrosineHMM predict
821O-linkedHMM predict
831Phosphoserine(ATM)HMM predict
884Phosphoserine(PKB)HMM predict
885Phosphoserine(ATM)HMM predict
924Phosphoserine(CK2)HMM predict
982Phosphoserine(ATM)HMM predict
1071Phosphoserine(ATM)HMM predict
1108Phosphoserine(CDC2)HMM predict
1134Phosphoserine(PKG)HMM predict
1141Phosphotyrosine(SRC)HMM predict
1259Phosphoserine(CK1)HMM predict
1299Phosphoserine(PKB)HMM predict
1318Phosphoserine(PKG)HMM predict
1318Phosphoserine(PKA)HMM predict
1318Phosphoserine(PKA)HMM predict
1318Phosphoserine(IKK)HMM predict
1326Phosphoserine(IKK)HMM predict
1327Phosphoserine(CDC2)HMM predict
1372Phosphoserine(CDK)HMM predict
1372Phosphoserine(CDC2)HMM predict
1372O-linkedHMM predict
1440S-palmitoylHMM predict
1469Phosphoserine(CDC2)HMM predict
1495Phosphoserine(PKG)HMM predict
1495Phosphoserine(PKA)HMM predict
1520Phosphothreonine(PKC)HMM predict
1527Phosphothreonine(PKC)HMM predict
1567O-linkedHMM predict
1669Phosphoserine(CAMK2)HMM predict
1715Phosphothreonine(CDC2)HMM predict
1747Phosphoserine(ATM)HMM predict
1780Phosphothreonine(PKA)HMM predict
2027Phosphoserine(CK1)HMM predict
2059Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018