AutismKB 2.0

Annotation Detail for AMD1


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Basic Information Top
Gene Symbol:AMD1 ( ADOMETDC,AMD,DKFZp313L1234,FLJ26964,SAMDC )
Gene Full Name: adenosylmethionine decarboxylase 1
Band: 6q21
Quick LinksEntrez ID:262; OMIM: 180980; Uniprot ID:DCAM_HUMAN; ENSEMBL ID: ENSG00000123505; HGNC ID: 457
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
68Pyruvic acid (Ser); by autocatalysis.
298Phosphoserine.
Location(AA) Modifications Resource
68Pyruvic acid (Ser).Swiss-Prot 53.0
Location(AA) Modification Resource
171Phosphoserine(CK1)HMM predict
252Phosphotyrosine(EGFR)HMM predict
258N-linkedHMM predict
298Phosphoserine(CDC2)HMM predict
298Phosphoserine(CDK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001033059
  • Location:chr6 111302680-111323605
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 111307090 111307352 262 0
CTCF CD4SISSRdata 111307090 111307352 262 0
CTCF G2GSE9613 111302146 111304391 2245 0
Fos K562GSE19551 111302250 111303254 1004 0
H3ac HepG2E 111304137 111304571 434 0
H3ac HepG2E 111304999 111305705 706 0
NFkBII GM15510GSE19485 111301768 111305412 3644 0
PHF8 293TGSE20725 111301963 111304543 2580 0
PHF8 Hs68plusFBSGSE20725 111301992 111304689 2697 0
Pol2 GM12878GSE19551 111301862 111304469 2607 0
PolII HeLaGSE12783 111301476 111305628 4152 0
TAF k562GSE8489 111304213 111305393 1180 0
hScc1 BcellGSE12603 111303001 111303359 358 0
hScc1 CdLSGSE12603 111307261 111307623 362 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018