AutismKB 2.0

Annotation Detail for FBXL6


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:FBXL6 ( FBL6,FBL6A,PP14630 )
Gene Full Name: F-box and leucine-rich repeat protein 6
Band: 8q24.3
Quick LinksEntrez ID:26233; OMIM: 609076; Uniprot ID:FBXL6_HUMAN; ENSEMBL ID: ENSG00000182325; HGNC ID: 13603
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
64Phosphoserine(PKG)HMM predict
67Phosphothreonine(CDK)HMM predict
76Phosphoserine(PKB)HMM predict
100O-linkedHMM predict
100O-linkedHMM predict
100O-linkedHMM predict
100Phosphothreonine(MAPK)HMM predict
102O-linkedHMM predict
152Phosphoserine(ATM)HMM predict
161Phosphothreonine(CDK)HMM predict
164Phosphoserine(MAPK)HMM predict
164Phosphoserine(CDC2)HMM predict
218S-palmitoylHMM predict
219S-palmitoylHMM predict
282O-linkedHMM predict
347MethylarginineHMM predict
398Phosphothreonine(PKA)HMM predict
448Phosphoserine(ATM)HMM predict
486Phosphothreonine(MAPK)HMM predict
486Phosphothreonine(PKA)HMM predict
488O-linkedHMM predict
488O-linkedHMM predict
488Phosphoserine(IKK)HMM predict
489O-linkedHMM predict
491O-linkedHMM predict
492O-linkedHMM predict
535Phosphoserine(CDC2)HMM predict
535Phosphoserine(ATM)HMM predict
535Phosphoserine(CDK)HMM predict
535Phosphoserine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_012162
  • Location:chr8 145549899-145552939
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NFkBII GM15510GSE19485 145552353 145553600 1247 37
PHF8 HeLaGSE20725 145551634 145554298 2664 27
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 145546006 145546173 167 3810
CTCF CD4SISSRdata 145546006 145546173 167 3810
CTCF JurkatGSE12889 145546033 145546320 287 3723
NRSF pAbJurkat 145547909 145548409 500 1741
hScc1 BcellGSE12603 145545622 145546220 598 3979
hScc1 CdLSGSE12603 145545725 145546255 530 3910
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF pAbJurkat 145549511 145550421 910 0
NRSF pAbJurkat 145550811 145551384 573 0
PHF8 293TGSE20725 145552381 145553470 1089 0
hScc1 BcellGSE12603 145552313 145553437 1124 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018