AutismKB 2.0

Annotation Detail for FBXL4


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Basic Information Top
Gene Symbol:FBXL4 ( FBL4,FBL5 )
Gene Full Name: F-box and leucine-rich repeat protein 4
Band: 6q16.1-q16.2
Quick LinksEntrez ID:26235; OMIM: 605654; Uniprot ID:FBXL4_HUMAN; ENSEMBL ID: ENSG00000112234; HGNC ID: 13601
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
42Phosphoserine(IKK)HMM predict
42Phosphoserine(ATM)HMM predict
45Phosphoserine(CDK)HMM predict
117Phosphothreonine(MAPK)HMM predict
126Phosphotyrosine(EGFR)HMM predict
136Phosphotyrosine(EGFR)HMM predict
162Phosphotyrosine(Jak)HMM predict
163Phosphoserine(ATM)HMM predict
163O-linkedHMM predict
184N-linkedHMM predict
210N-linkedHMM predict
216SulfotyrosineHMM predict
251Phosphotyrosine(INSR)HMM predict
251SulfotyrosineHMM predict
251Phosphotyrosine(Syk)HMM predict
351N-linkedHMM predict
357N-linkedHMM predict
389N-linkedHMM predict
407N-linkedHMM predict
491N-linkedHMM predict
495N-linkedHMM predict
520O-linkedHMM predict
543N-linkedHMM predict
557N-linkedHMM predict
573Phosphoserine(CAMK2)HMM predict
593Phosphoserine(IKK)HMM predict
607N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_012160
  • Location:chr6 99428321-99502569
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 99511919 99512474 555 9627
Oct1 H2O2-HelaGSE14283 99511280 99511313 33 8727
Oct1 HelaGSE14283 99511284 99511314 30 8730
P300 T30-glioblastomaGSE21026 99511791 99512448 657 9550
p130 QuiescentGSE19898 99520065 99520234 169 17580
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
P300 T0-glioblastomaGSE21026 99425346 99426229 883 2534
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 99501855 99502475 620 0
ER E2-MCF7GSE14664 99446020 99446053 33 0
FoxA1 MCF7MACSdata 99499107 99499440 333 0
H3K4me3 colorectalcancer 99500883 99502061 1178 0
H3ac HepG2E 99500849 99501890 1041 0
Oct1 H2O2-HelaGSE14283 99438249 99438282 33 0
Oct1 H2O2-HelaGSE14283 99494895 99494922 27 0
Oct1 HelaGSE14283 99440314 99440340 26 0
Oct1 HelaGSE14283 99446016 99446064 48 0
Oct1 HelaGSE14283 99453694 99453733 39 0
Oct1 HelaGSE14283 99497905 99497982 77 0
PHF8 293TGSE20725 99501928 99502927 999 0
PHF8 Hs68plusFBSGSE20725 99501511 99502989 1478 0
TAF HelaGSE8489 99500883 99502026 1143 0
TAF k562GSE8489 99498552 99498849 297 0
TAF k562GSE8489 99500508 99501996 1488 0
TFAP2C MCF7GSE21234 99496059 99496416 357 0
USF2 HepG2E 99462161 99462663 502 0
hScc1 BcellGSE12603 99502026 99502430 404 0
p130 QuiescentGSE19898 99501900 99502178 278 0
p130 SenescentGSE19898 99502029 99502194 165 0
p130 shRbSenescentGSE19898 99502028 99502195 167 0
Validated miRNA targets Top
Cis-Nats regulation Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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