AutismKB 2.0

Annotation Detail for GATA3


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Basic Information Top
Gene Symbol:GATA3 ( HDR,MGC2346,MGC5199,MGC5445 )
Gene Full Name: GATA binding protein 3
Band: 10p14
Quick LinksEntrez ID:2625; OMIM: 131320; Uniprot ID:GATA3_HUMAN; ENSEMBL ID: ENSG00000107485; HGNC ID: 4172
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
115Phosphoserine.
162Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
35Phosphotyrosine(Syk)HMM predict
35Phosphotyrosine(INSR)HMM predict
41Phosphotyrosine(MAPK)HMM predict
71Phosphothreonine(PKC)HMM predict
113N-linkedHMM predict
115Phosphoserine(CDC2)HMM predict
126O-linkedHMM predict
138O-linkedHMM predict
140Phosphoserine(CK1)HMM predict
140O-linkedHMM predict
142Phosphoserine(CK1)HMM predict
142Phosphoserine(ATM)HMM predict
156Phosphothreonine(CDK)HMM predict
156Phosphothreonine(MAPK)HMM predict
162Phosphoserine(IKK)HMM predict
166O-linkedHMM predict
168O-linkedHMM predict
168Phosphoserine(CK1)HMM predict
169Phosphothreonine(CDK)HMM predict
201Phosphoserine(IKK)HMM predict
212O-linkedHMM predict
221O-linkedHMM predict
259Phosphothreonine(PKC)HMM predict
271Phosphothreonine(MAPK)HMM predict
271Phosphothreonine(CDK)HMM predict
308Phosphoserine(PKA)HMM predict
308Phosphoserine(PKG)HMM predict
316Phosphoserine(IKK)HMM predict
355Phosphothreonine(PKC)HMM predict
363Phosphothreonine(PKC)HMM predict
401Phosphoserine(CK1)HMM predict
407Phosphoserine(ATM)HMM predict
413O-linkedHMM predict
418O-linkedHMM predict
426O-linkedHMM predict
427O-linkedHMM predict
429O-linkedHMM predict
435ProlineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001002295
  • Location:chr10 8136672-8157167
  • strand:+
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog hESGSE18292 8168403 8168835 432 11452
Oct1 H2O2-HelaGSE14283 8176444 8176489 45 19299
Oct1 HelaGSE14283 8176443 8176495 52 19302
RARA MCF7GSE15244 8166601 8167419 818 9843
RARG MCF7GSE15244 8162838 8163616 778 6060
RARG MCF7GSE15244 8166601 8167419 818 9843
TFAP2C MCF7GSE21234 8166614 8167551 937 9915
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 8140974 8141386 412 0
Oct1 HelaGSE14283 8142950 8142977 27 0
P300 T0-glioblastomaGSE21026 8141637 8142715 1078 0
P300 T30-glioblastomaGSE21026 8141700 8142932 1232 0
RARA MCF7GSE15244 8142027 8142428 401 0
RARG MCF7GSE15244 8141990 8142428 438 0
RARG MCF7GSE15244 8145428 8146701 1273 0
RARG MCF7GSE15244 8150742 8151117 375 0
RARG MCF7GSE15244 8151401 8151950 549 0
RARG MCF7GSE15244 8155525 8155938 413 0
TFAP2C MCF7GSE21234 8143942 8144379 437 0
hScc1 BcellGSE12603 8138731 8139136 405 0
hScc1 CdLSGSE12603 8138731 8139439 708 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-122 hsa-mir-122 18 21059207
hsa-miR-122* hsa-mir-122 18 21059207
hsa-miR-126 hsa-mir-126 9 19843690
hsa-miR-126* hsa-mir-126 9 19843690
hsa-miR-144 hsa-mir-144 17 20656931
hsa-miR-144* hsa-mir-144 17 20656931
hsa-miR-155 hsa-mir-155 21 20656931
hsa-miR-155* hsa-mir-155 21 20656931
hsa-miR-200b hsa-mir-200b 1 21059207
hsa-miR-200b* hsa-mir-200b 1 21059207
hsa-miR-200c hsa-mir-200c 12 21059207
hsa-miR-200c* hsa-mir-200c 12 21059207
hsa-miR-205 hsa-mir-205 1 21059207
hsa-miR-210 hsa-mir-210 11 19141645
hsa-miR-302a hsa-mir-302a 4 21059207
hsa-miR-302a* hsa-mir-302a 4 21059207
hsa-miR-302b hsa-mir-302b 4 21059207
hsa-miR-302b* hsa-mir-302b 4 21059207
hsa-miR-302c hsa-mir-302c 4 21059207
hsa-miR-302c* hsa-mir-302c 4 21059207
hsa-miR-302d hsa-mir-302d 4 21059207
hsa-miR-302d* hsa-mir-302d 4 21059207
hsa-miR-302f hsa-mir-302f 0 21059207
hsa-miR-373 hsa-mir-373 19 19141645
hsa-miR-373* hsa-mir-373 19 19141645
hsa-miR-375 hsa-mir-375 2 21059207
hsa-miR-451 hsa-mir-451 17 20656931
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018