AutismKB 2.0

Annotation Detail for NKX2-8


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Basic Information Top
Gene Symbol:NKX2-8 ( NKX2.8,NKX2H,Nkx2-9 )
Gene Full Name: NK2 homeobox 8
Band: 14q13.3
Quick LinksEntrez ID:26257; OMIM: 603245; Uniprot ID:NKX28_HUMAN; ENSEMBL ID: ENSG00000136327; HGNC ID: 16364
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
51SulfotyrosineHMM predict
54Phosphoserine(ATM)HMM predict
57Phosphoserine(CK1)HMM predict
57Phosphoserine(CK2)HMM predict
57Phosphoserine(IKK)HMM predict
58O-linkedHMM predict
58Phosphoserine(CK1)HMM predict
58Phosphoserine(IKK)HMM predict
62Phosphoserine(IKK)HMM predict
62Phosphoserine(ATM)HMM predict
66Phosphoserine(CDC2)HMM predict
67Phosphoserine(ATM)HMM predict
76Phosphoserine(MAPK)HMM predict
76Phosphoserine(IKK)HMM predict
76O-linkedHMM predict
231Phosphoserine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014360
  • Location:chr14 36118967-36121536
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 36131627 36131661 34 10108
H3K27me3 colorectalcancer 36123605 36124360 755 2446
H3K27me3 colorectalcancer 36128694 36129019 325 7320
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 CdLSGSE12603 36107311 36107529 218 11548
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 36119099 36119417 318 0
hScc1 BcellGSE12603 36119136 36119417 281 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018