AutismKB 2.0

Annotation Detail for ARFGAP3


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Basic Information Top
Gene Symbol:ARFGAP3 ( ARFGAP1,FLJ45618 )
Gene Full Name: ADP-ribosylation factor GTPase activating protein 3
Band: 22q13.2
Quick LinksEntrez ID:26286; OMIM: 612439; Uniprot ID:ARFG3_HUMAN; ENSEMBL ID: ENSG00000100266,ENSG00000242247; HGNC ID: 661
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
143Phosphoserine.
223N6-acetyllysine.
228N6-acetyllysine.
229N6-acetyllysine.
270Phosphoserine.
331Phosphoserine.
370Phosphoserine.
428Phosphoserine.
453Phosphoserine.
Location(AA) Modifications Resource
143Phosphoserine.Swiss-Prot 53.0
143PhosphoserinePhospho.ELM 6.0
349PhosphotyrosinePhospho.ELM 6.0
Location(AA) Modification Resource
18Phosphoserine(PKA)HMM predict
32N-linkedHMM predict
34PhosphoserineHMM predict
70N-linkedHMM predict
84N-linkedHMM predict
99N-linkedHMM predict
102N-linkedHMM predict
125Phosphothreonine(PKC)HMM predict
143Phosphoserine(CDK)HMM predict
143Phosphoserine(CDC2)HMM predict
143Phosphoserine(MAPK)HMM predict
163O-linkedHMM predict
177O-linkedHMM predict
207Phosphothreonine(PKA)HMM predict
270Phosphoserine(IKK)HMM predict
321Phosphothreonine(PKA)HMM predict
341Phosphotyrosine(Syk)HMM predict
355Phosphoserine(CK2)HMM predict
370Phosphoserine(IKK)HMM predict
384Phosphoserine(CK2)HMM predict
384Phosphoserine(CK1)HMM predict
396Phosphotyrosine(Jak)HMM predict
401Phosphothreonine(PKC)HMM predict
408Phosphotyrosine(EGFR)HMM predict
408Phosphotyrosine(SRC)HMM predict
437Phosphoserine(PKG)HMM predict
441Phosphotyrosine(Syk)HMM predict
451PhosphoserineHMM predict
453O-linkedHMM predict
472N-linkedHMM predict
508ThreonineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014570
  • Location:chr22 41522475-41583243
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 41506102 41506347 245 16251
CTCF CD4SISSRdata 41506102 41506347 245 16251
CTCF G2GSE9613 41512868 41513760 892 9162
Nanog hESGSE18292 41506084 41506297 213 16285
STAT1 IFNSISSRdata 41506047 41506497 450 16204
Sox2 hESGSE18292 41506093 41506549 456 16155
hScc1 BcellGSE12603 41506115 41506398 283 16219
hScc1 BcellGSE12603 41511467 41511839 372 10823
hScc1 BcellGSE12603 41512981 41513293 312 9339
hScc1 BcellGSE12603 41517587 41517892 305 4736
hScc1 BcellGSE12603 41520047 41521006 959 1949
hScc1 CdLSGSE12603 41506115 41506398 283 16219
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 41582459 41583600 1141 0
ER MCF7GSE19013 41526564 41527581 1017 0
FOXA1 MCF7GSE15244 41531057 41531660 603 0
FOXA1 MCF7GSE15244 41545537 41546340 803 0
H3ac HepG2E 41582020 41582420 400 0
PHF8 293TGSE20725 41582615 41583592 977 0
PHF8 Hs68plusFBSGSE20725 41581501 41583370 1869 0
RARA MCF7GSE15244 41531057 41531660 603 0
RARG MCF7GSE15244 41531057 41531660 603 0
STAT1 HeLaGSE12782 41570193 41571684 1491 0
STAT1 HeLaGSE12783 41570374 41571650 1276 0
STAT1 IFNSISSRdata 41570470 41571316 846 0
TFAP2C MCF7GSE21234 41529348 41529948 600 0
hScc1 BcellGSE12603 41531504 41531848 344 0
hScc1 BcellGSE12603 41545971 41546377 406 0
hScc1 BcellGSE12603 41582160 41583600 1440 0
hScc1 CdLSGSE12603 41582611 41583600 989 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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