AutismKB 2.0

Annotation Detail for GBP1


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Basic Information Top
Gene Symbol:GBP1 ( - )
Gene Full Name: guanylate binding protein 1, interferon-inducible, 67kDa
Band: 1p22.2
Quick LinksEntrez ID:2633; OMIM: 600411; Uniprot ID:GBP1_HUMAN; ENSEMBL ID: ENSG00000117228; HGNC ID: 4182
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
589Cysteine methyl ester.
Location(AA) Modifications Resource
589S-farnesyl cysteine.Swiss-Prot 53.0
Location(AA) Modification Resource
144SulfotyrosineHMM predict
154Phosphoserine(CK1)HMM predict
156Phosphoserine(PKB)HMM predict
157Phosphoserine(IKK)HMM predict
157Phosphoserine(CDC2)HMM predict
197Phosphothreonine(MAPK)HMM predict
201Phosphotyrosine(Jak)HMM predict
416Phosphoserine(CDC2)HMM predict
427Phosphotyrosine(INSR)HMM predict
448Phosphotyrosine(Syk)HMM predict
448Phosphotyrosine(EGFR)HMM predict
483Phosphothreonine(CK2)HMM predict
524Phosphotyrosine(EGFR)HMM predict
581Phosphothreonine(PKC)HMM predict
589S-farnesylHMM predict
591IsoleucineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002053
  • Location:chr1 89290593-89303478
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
STAT1 HeLaGSE12783 89307884 89309045 1161 4986
STAT1 IFNSISSRdata 89308034 89309185 1151 5131
No data
No data
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018