AutismKB 2.0

Annotation Detail for GBP2


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Basic Information Top
Gene Symbol:GBP2 ( - )
Gene Full Name: guanylate binding protein 2, interferon-inducible
Band: 1p22.2
Quick LinksEntrez ID:2634; OMIM: 600412; Uniprot ID:GBP2_HUMAN; ENSEMBL ID: ENSG00000162645; HGNC ID: 4183
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
588Cysteine methyl ester (By similarity).
Location(AA) Modifications Resource
588S-geranylgeranyl cysteine (Bysimilarity).Swiss-Prot 53.0
Location(AA) Modification Resource
144SulfotyrosineHMM predict
155N-linkedHMM predict
157Phosphoserine(CDC2)HMM predict
160N-linkedHMM predict
161N-linkedHMM predict
216Phosphoserine(IKK)HMM predict
445Phosphotyrosine(Syk)HMM predict
481Phosphoserine(CK2)HMM predict
522Phosphotyrosine(EGFR)HMM predict
589AsparagineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004120
  • Location:chr1 89345897-89364386
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 89329420 89329463 43 16456
Oct1 HelaGSE14283 89329421 89329463 42 16456
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 89364118 89364581 463 0
H3K4me3 colorectalcancer 89363536 89363849 313 0
P300 T30-glioblastomaGSE21026 89363786 89364840 1054 0
SRF HelaGSE8489 89362918 89364721 1803 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018