AutismKB 2.0

Annotation Detail for AATF


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Basic Information Top
Gene Symbol:AATF ( CHE-1,CHE1,DED )
Gene Full Name: apoptosis antagonizing transcription factor
Band: 17q12
Quick LinksEntrez ID:26574; OMIM: 608463; Uniprot ID:AATF_HUMAN; ENSEMBL ID: ENSG00000108270; HGNC ID: 19235
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
203Phosphoserine.
316Phosphoserine.
320Phosphoserine.
321Phosphoserine.
Location(AA) Modifications Resource
117PhosphotyrosinePhospho.ELM 6.0
203Phosphoserine.Swiss-Prot 53.0
203PhosphoserinePhospho.ELM 6.0
316Phosphoserine.Swiss-Prot 53.0
316PhosphoserinePhospho.ELM 6.0
320Phosphoserine.Swiss-Prot 53.0
320PhosphoserinePhospho.ELM 6.0
321Phosphoserine.Swiss-Prot 53.0
321PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
93Phosphoserine(CK2)HMM predict
94Phosphoserine(CK2)HMM predict
99PhosphoserineHMM predict
99Phosphoserine(CK1)HMM predict
99Phosphoserine(CK2)HMM predict
104Phosphoserine(CK1)HMM predict
104Phosphoserine(CK2)HMM predict
117Phosphotyrosine(Syk)HMM predict
117Phosphotyrosine(INSR)HMM predict
143Phosphoserine(IKK)HMM predict
169Phosphoserine(CK1)HMM predict
169Phosphoserine(CK2)HMM predict
169PhosphoserineHMM predict
170Phosphoserine(CK2)HMM predict
178Phosphoserine(CK2)HMM predict
189Phosphoserine(ATM)HMM predict
218Phosphoserine(PKG)HMM predict
320Phosphoserine(CK2)HMM predict
320Phosphoserine(CK1)HMM predict
321Phosphoserine(CK1)HMM predict
348Phosphotyrosine(EGFR)HMM predict
364N-linkedHMM predict
412Phosphothreonine(PKC)HMM predict
477Phosphoserine(IKK)HMM predict
477Phosphoserine(PKG)HMM predict
478Phosphoserine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_012138
  • Location:chr17 32380287-32488282
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 32378144 32378927 783 1752
Rb GrowingGSE19898 32380123 32380391 268 31
Rb QuiescentGSE19898 32380054 32380456 402 33
Rb SenescentGSE19898 32379972 32380505 533 49
Rb shRbQuiescentGSE19898 32380159 32380406 247 5
Rb shRbSenescenceGSE19898 32379979 32380356 377 120
USF1 HepG2E 32378419 32380316 1897 920
USF2 HepG2E 32379107 32380174 1067 647
hScc1 BcellGSE12603 32379897 32380433 536 123
p130 QuiescentGSE19898 32379998 32380403 405 87
p130 shRbQuiescentGSE19898 32379754 32380594 840 114
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 32499866 32500005 139 11653
P300 T30-glioblastomaGSE21026 32498961 32499734 773 11065
RARA MCF7GSE15244 32498678 32499705 1027 10909
RARG MCF7GSE15244 32498749 32499597 848 10891
TFAP2C MCF7GSE21234 32492464 32492756 292 4328
hScc1 BcellGSE12603 32497744 32498116 372 9648
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 32479054 32479475 421 0
CTCF CD4SISSRdata 32479054 32479475 421 0
CTCF G2GSE9613 32478970 32479514 544 0
ETS1 JurkatGSE17954 32379638 32380986 1348 0
H3K4me3 colorectalcancer 32380780 32381164 384 0
H3ac HepG2E 32380861 32381164 303 0
H3ac HepG2E 32385802 32386249 447 0
KLF4 hESGSE17917 32476734 32476928 194 0
Myc K562GSE19551 32479040 32479405 365 0
Oct1 H2O2-HelaGSE14283 32475990 32476017 27 0
Oct1 HelaGSE14283 32384281 32384316 35 0
PHF8 HeLaGSE20725 32379537 32381280 1743 0
USF1 HepG2E 32380926 32381164 238 0
hScc1 BcellGSE12603 32479012 32479586 574 0
hScc1 CdLSGSE12603 32478935 32479622 687 0
hScc1 G2GSE9613 32478863 32479622 759 0
p130 QuiescentGSE19898 32380446 32380667 221 0
p130 SenescentGSE19898 32380123 32380667 544 0
p130 SenescentGSE19898 32380799 32380997 198 0
p130 shRbSenescentGSE19898 32379919 32380707 788 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-149 hsa-mir-149 2 19082544
hsa-miR-149* hsa-mir-149 2 19082544
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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