AutismKB 2.0

Annotation Detail for GREM1


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Basic Information Top
Gene Symbol:GREM1 ( CKTSF1B1,DAND2,DRM,GREMLIN,IHG-2,MGC126660 )
Gene Full Name: gremlin 1
Band: 15q13.3
Quick LinksEntrez ID:26585; OMIM: 603054; Uniprot ID:GREM1_HUMAN; ENSEMBL ID: ENSG00000166923; HGNC ID: 2001
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
42N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
42N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
6Phosphotyrosine(INSR)HMM predict
29Phosphoserine(PKA)HMM predict
42N-linkedHMM predict
44Phosphoserine(CK1)HMM predict
47O-linkedHMM predict
49Phosphoserine(CDC2)HMM predict
49Phosphoserine(IKK)HMM predict
56MethylarginineHMM predict
58MethylarginineHMM predict
64MethylarginineHMM predict
150Phosphothreonine(PKA)HMM predict
171Phosphothreonine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_013372
  • Location:chr15 30797496-30814157
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 30794861 30796698 1837 1717
P300 T30-glioblastomaGSE21026 30794860 30795435 575 2349
p130 QuiescentGSE19898 30797341 30797528 187 62
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 30817580 30817922 342 3594
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 30797293 30797885 592 0
CTCF G2GSE9613 30810147 30810366 219 0
Oct1 HelaGSE14283 30808014 30808049 35 0
hScc1 BcellGSE12603 30796981 30798370 1389 0
hScc1 BcellGSE12603 30810147 30810333 186 0
p130 shRbSenescentGSE19898 30797328 30797813 485 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-491-3p hsa-mir-491 9 21128281
hsa-miR-491-5p hsa-mir-491 9 21128281
hsa-miR-646 hsa-mir-646 20 21128281
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
8602 mRNA GREM1 chr15 30797593 30814158 61 EST chr15 30797593 30798274Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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