AutismKB 2.0

Annotation Detail for GFRA2


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Basic Information Top
Gene Symbol:GFRA2 ( GDNFRB,NRTNR-ALPHA,NTNRA,RETL2,TRNR2 )
Gene Full Name: GDNF family receptor alpha 2
Band: 8p21.3
Quick LinksEntrez ID:2675; OMIM: 601956; Uniprot ID:GFRA2_HUMAN; ENSEMBL ID: ENSG00000168546; HGNC ID: 4244
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
52N-linked (GlcNAc...) (Potential).
357N-linked (GlcNAc...) (Potential).
413N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
52N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
357N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
413N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
444GPI-anchor amidated serine (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
22Phosphoserine(MAPK)HMM predict
22Phosphoserine(CDC2)HMM predict
22Phosphoserine(CDK)HMM predict
52N-linkedHMM predict
59Phosphothreonine(PKC)HMM predict
123Phosphotyrosine(EGFR)HMM predict
123Phosphotyrosine(Syk)HMM predict
128Phosphotyrosine(SRC)HMM predict
128Phosphotyrosine(Syk)HMM predict
148O-linkedHMM predict
224S-palmitoylHMM predict
236Phosphothreonine(PKG)HMM predict
243Phosphotyrosine(Syk)HMM predict
283O-linkedHMM predict
309SulfotyrosineHMM predict
313Phosphoserine(CDK)HMM predict
313Phosphoserine(CDC2)HMM predict
357N-linkedHMM predict
362N-linkedHMM predict
364Phosphoserine(CDC2)HMM predict
364Phosphoserine(CDK)HMM predict
389Phosphoserine(CK2)HMM predict
389Phosphoserine(CK1)HMM predict
393Phosphoserine(IKK)HMM predict
393Phosphoserine(CK1)HMM predict
400O-linkedHMM predict
401O-linkedHMM predict
403O-linkedHMM predict
413N-linkedHMM predict
414N-linkedHMM predict
445MethylarginineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001495
  • Location:chr8 21593811-21702291
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 21702675 21703608 933 850
H3K27me3 colorectalcancer 21704623 21705474 851 2757
H3K27me3 colorectalcancer 21705932 21706215 283 3782
H3K27me3 colorectalcancer 21706541 21706939 398 4449
NRSF pAbJurkat 21702609 21702973 364 500
P300 T30-glioblastomaGSE21026 21702070 21702657 587 72
hScc1 BcellGSE12603 21702609 21702783 174 405
hScc1 CdLSGSE12603 21708440 21708650 210 6254
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 21585493 21586419 926 7856
CTCF G2GSE9613 21575101 21575231 130 18646
CTCF G2GSE9613 21584785 21585221 436 8809
CTCF G2GSE9613 21591117 21591268 151 2619
FOXA1 MCF7GSE15244 21581369 21581640 271 12307
FOXA1 MCF7GSE15244 21585733 21586217 484 7837
FOXA1 MCF7GSE15244 21588296 21589736 1440 4796
P300 T0-glioblastomaGSE21026 21576345 21576789 444 17245
P300 T30-glioblastomaGSE21026 21585410 21586400 990 7907
RARA MCF7GSE15244 21585591 21586217 626 7908
RARG MCF7GSE15244 21585694 21586217 523 7856
Stat6 IL-4-hr1GSE17850 21577772 21578260 488 15796
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 21697877 21698167 290 0
CTCF CD4SISSRdata 21697877 21698167 290 0
CTCF JurkatGSE12889 21697822 21698217 395 0
CTCF G2GSE9613 21594327 21594939 612 0
CTCF G2GSE9613 21596174 21596883 709 0
CTCF G2GSE9613 21599817 21600108 291 0
CTCF G2GSE9613 21601043 21601950 907 0
CTCF G2GSE9613 21603672 21604098 426 0
CTCF G2GSE9613 21605993 21606332 339 0
CTCF G2GSE9613 21609029 21609361 332 0
CTCF G2GSE9613 21611414 21612668 1254 0
CTCF G2GSE9613 21620762 21621070 308 0
CTCF G2GSE9613 21624185 21624567 382 0
CTCF G2GSE9613 21629114 21629447 333 0
CTCF G2GSE9613 21641785 21642326 541 0
CTCF G2GSE9613 21645936 21646112 176 0
CTCF G2GSE9613 21647483 21647773 290 0
CTCF G2GSE9613 21652259 21653448 1189 0
CTCF G2GSE9613 21662944 21663215 271 0
CTCF G2GSE9613 21681999 21682346 347 0
CTCF G2GSE9613 21687457 21687834 377 0
CTCF G2GSE9613 21688397 21689218 821 0
CTCF G2GSE9613 21689737 21689899 162 0
CTCF G2GSE9613 21695514 21697096 1582 0
CTCF G2GSE9613 21697541 21698528 987 0
CTCF G2GSE9613 21700926 21701968 1042 0
FOXA1 MCF7GSE15244 21646040 21647050 1010 0
H3K27me3 colorectalcancer 21701926 21702225 299 0
NRSF pAbJurkat 21601043 21601328 285 0
NRSF pAbJurkat 21650328 21650807 479 0
NRSF pAbJurkat 21657583 21657754 171 0
NRSF pAbJurkat 21684051 21684456 405 0
NRSF pAbJurkat 21696589 21696771 182 0
NRSF pAbJurkat 21697359 21697732 373 0
NRSF pAbJurkat 21700780 21701183 403 0
P300 T30-glioblastomaGSE21026 21658313 21659182 869 0
RARA MCF7GSE15244 21646015 21647050 1035 0
RARG MCF7GSE15244 21642114 21642858 744 0
RARG MCF7GSE15244 21646040 21647083 1043 0
TAF HelaGSE8489 21650047 21650613 566 0
TFAP2C MCF7GSE21234 21626758 21627169 411 0
TFAP2C MCF7GSE21234 21642459 21642847 388 0
hScc1 BcellGSE12603 21600141 21600696 555 0
hScc1 BcellGSE12603 21603821 21604098 277 0
hScc1 BcellGSE12603 21611340 21611645 305 0
hScc1 BcellGSE12603 21618202 21618445 243 0
hScc1 BcellGSE12603 21634878 21635014 136 0
hScc1 BcellGSE12603 21637757 21638013 256 0
hScc1 BcellGSE12603 21639354 21639798 444 0
hScc1 BcellGSE12603 21650571 21650744 173 0
hScc1 BcellGSE12603 21694570 21694785 215 0
hScc1 BcellGSE12603 21697483 21698564 1081 0
hScc1 BcellGSE12603 21699208 21699629 421 0
hScc1 BcellGSE12603 21701230 21701601 371 0
hScc1 CdLSGSE12603 21697483 21698494 1011 0
hScc1 G2GSE9613 21613034 21613315 281 0
hScc1 G2GSE9613 21697323 21698528 1205 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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