AutismKB 2.0

Annotation Detail for OPLAH


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Basic Information Top
Gene Symbol:OPLAH ( 5-Opase,DKFZp434H244,OPLA )
Gene Full Name: 5-oxoprolinase (ATP-hydrolysing)
Band: 8q24.3
Quick LinksEntrez ID:26873; OMIM: NA; Uniprot ID:OPLA_HUMAN; ENSEMBL ID: ENSG00000178814; HGNC ID: 8149
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
43Phosphotyrosine(Syk)HMM predict
151Phosphothreonine(CDC2)HMM predict
419Phosphoserine(MAPK)HMM predict
419Phosphoserine(CDC2)HMM predict
446Phosphoserine(CDC2)HMM predict
446Phosphoserine(MAPK)HMM predict
449Phosphoserine(CK1)HMM predict
602Phosphoserine(CDC2)HMM predict
639Phosphothreonine(PKA)HMM predict
639Phosphothreonine(PKC)HMM predict
671Phosphotyrosine(EGFR)HMM predict
677Phosphotyrosine(SRC)HMM predict
698N-linkedHMM predict
909N-linkedHMM predict
915N-linkedHMM predict
921Phosphoserine(CK1)HMM predict
1005Phosphoserine(ATM)HMM predict
1031Phosphothreonine(PKA)HMM predict
1031Phosphothreonine(PKC)HMM predict
1138PhosphoserineHMM predict
1171MethylarginineHMM predict
1175MethylarginineHMM predict
1234Phosphoserine(PKG)HMM predict
1253Phosphotyrosine(EGFR)HMM predict
1253Phosphotyrosine(INSR)HMM predict
1253Phosphotyrosine(Abl)HMM predict
1265O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_017570
  • Location:chr8 145178155-145186958
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF pAbJurkat 145186517 145188014 1497 307
NRSF pAbJurkat 145189491 145190311 820 2943
NRSF pAbJurkat 145191169 145191704 535 4478
TFAP2C MCF7GSE21234 145190132 145190737 605 3476
hScc1 BcellGSE12603 145186997 145187857 860 469
hScc1 BcellGSE12603 145189422 145190975 1553 3240
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF pAbJurkat 145176132 145177922 1790 1129
hScc1 CdLSGSE12603 145175745 145177327 1582 1620
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER MCF7GSE19013 145178935 145179430 495 0
NRSF pAbJurkat 145179115 145180241 1126 0
NRSF pAbJurkat 145180490 145181541 1051 0
NRSF pAbJurkat 145182916 145183348 432 0
TFAP2C MCF7GSE21234 145179628 145180069 441 0
hScc1 BcellGSE12603 145178981 145179593 612 0
hScc1 BcellGSE12603 145180490 145181011 521 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
26095 EST chr8 145177435 145178506 197 mRNA OPLAH chr8 145178164 145186923Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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