AutismKB 2.0

Annotation Detail for PABPC1


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Basic Information Top
Gene Symbol:PABPC1 ( PAB1,PABP,PABP1,PABPC2,PABPL1 )
Gene Full Name: poly(A) binding protein, cytoplasmic 1
Band: 8q22.3
Quick LinksEntrez ID:26986; OMIM: 604679; Uniprot ID:PABP1_HUMAN; ENSEMBL ID: ENSG00000070756; HGNC ID: 8554
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1N-acetylmethionine.
96Phosphoserine.
116Phosphotyrosine (By similarity).
299N6-methyllysine.
315Phosphoserine.
319Phosphothreonine.
342Phosphoserine.
364Phosphotyrosine.
455Omega-N-methylated arginine; by CARM1;
460Omega-N-methylated arginine; by CARM1;
493Dimethylated arginine; alternate.
493Omega-N-methylarginine; alternate.
512N6-acetyllysine.
Location(AA) Modifications Resource
54PhosphotyrosinePhospho.ELM 6.0
364Phosphotyrosine.Swiss-Prot 53.0
364PhosphotyrosinePhospho.ELM 6.0
455Omega-N-methylated arginine; by CARM1;partial (Probable).Swiss-Prot 53.0
460Omega-N-methylated arginine; by CARM1;partial (Probable).Swiss-Prot 53.0
493Omega-N-methylated arginine.Swiss-Prot 53.0
Location(AA) Modification Resource
32Phosphoserine(CDC2)HMM predict
92Phosphoserine(PKB)HMM predict
92Phosphoserine(PKC)HMM predict
135N-linkedHMM predict
315Phosphoserine(CDC2)HMM predict
342Phosphoserine(CDC2)HMM predict
364Phosphotyrosine(Jak)HMM predict
434Phosphoserine(CDC2)HMM predict
464O-linkedHMM predict
464O-linkedHMM predict
502Phosphothreonine(MAPK)HMM predict
548Phosphoserine(IKK)HMM predict
599PhosphoserineHMM predict
602Phosphoserine(CDK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002568
  • Location:chr8 101784319-101803490
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 101802904 101804655 1751 289
H3K4me3 colorectalcancer 101804559 101804975 416 1277
NFkBII GM15510GSE19485 101802897 101804425 1528 171
Oct1 H2O2-HelaGSE14283 101820319 101820354 35 16846
PHF8 Hs68plusFBSGSE20725 101802876 101804642 1766 269
RARA MCF7GSE15244 101805505 101805827 322 2176
Rb QuiescentGSE19898 101803704 101804084 380 404
Rb SenescentGSE19898 101803726 101804038 312 392
Rb shRbSenescenceGSE19898 101803627 101803842 215 244
STAT1 HeLaGSE12783 101810188 101812229 2041 7718
hScc1 BcellGSE12603 101802941 101804273 1332 117
hScc1 G2GSE9613 101802974 101804217 1243 105
p130 QuiescentGSE19898 101803425 101803568 143 6
p130 SenescentGSE19898 101803718 101804113 395 425
p130 shRbSenescentGSE19898 101803336 101804163 827 259
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
RARA MCF7GSE15244 101781302 101781687 385 2825
RARG MCF7GSE15244 101780729 101780955 226 3478
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 101802172 101804249 2077 0
ER Breast-CancerGSE22609 101801088 101801600 512 0
H3K4me3 colorectalcancer 101801119 101802134 1015 0
H3ac HepG2E 101801080 101802277 1197 0
PHF8 HeLaGSE20725 101801961 101804678 2717 0
Pol2 GM12878GSE19551 101802786 101803665 879 0
RARA MCF7GSE15244 101800930 101802237 1307 0
RARG MCF7GSE15244 101801582 101802134 552 0
Rb SenescentGSE19898 101803383 101803534 151 0
VDR GM10855-stimGSE22484 101797517 101804724 7207 0
VDR GM10861-stimGSE22484 101798730 101804804 6074 0
hScc1 CdLSGSE12603 101801715 101804217 2502 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
25768 EST chr8 101802733 101803351 557 mRNA PABPC1 chr8 101784319 101803491Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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