AutismKB 2.0

Annotation Detail for USP21


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Basic Information Top
Gene Symbol:USP21 ( MGC3394,USP16,USP23 )
Gene Full Name: ubiquitin specific peptidase 21
Band: 1q23.3
Quick LinksEntrez ID:27005; OMIM: 604729; Uniprot ID:UBP21_HUMAN; ENSEMBL ID: ENSG00000143258; HGNC ID: 12620
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
79MethylarginineHMM predict
93Phosphoserine(CDC2)HMM predict
93O-linkedHMM predict
93Phosphoserine(IKK)HMM predict
97O-linkedHMM predict
113Phosphoserine(PKB)HMM predict
113Phosphoserine(IKK)HMM predict
132Phosphothreonine(PKA)HMM predict
150Phosphothreonine(PKC)HMM predict
156Phosphoserine(PKC)HMM predict
231Phosphoserine(CDC2)HMM predict
279N-linkedHMM predict
297Phosphotyrosine(INSR)HMM predict
298Phosphoserine(ATM)HMM predict
335Phosphoserine(CDC2)HMM predict
350Phosphoserine(CK2)HMM predict
368Phosphoserine(CK1)HMM predict
444Phosphothreonine(PKA)HMM predict
447Phosphothreonine(PKA)HMM predict
476Phosphoserine(CDC2)HMM predict
499Phosphoserine(CDK)HMM predict
502Phosphotyrosine(SRC)HMM predict
509N-linkedHMM predict
525S-palmitoylHMM predict
533N-linkedHMM predict
538Phosphoserine(MAPK)HMM predict
538Phosphoserine(CDC2)HMM predict
551Phosphotyrosine(INSR)HMM predict
558MethionineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001014443
  • Location:chr1 159395877-159402138
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 159395579 159396104 525 36
Rb SenescentGSE19898 159395608 159396126 518 11
p130 SenescentGSE19898 159395464 159395954 490 169
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 159396388 159397082 694 0
H3ac HepG2E 159399666 159401177 1511 0
P300 T30-glioblastomaGSE21026 159395264 159396830 1566 0
Rb GrowingGSE19898 159395798 159396273 475 0
Rb QuiescentGSE19898 159395743 159396022 279 0
TAF k562GSE8489 159396388 159397002 614 0
TAF k562GSE8489 159399369 159400181 812 0
TAFII hESGSE17917 159395496 159396430 934 0
hScc1 BcellGSE12603 159395966 159396278 312 0
p130 QuiescentGSE19898 159395870 159396117 247 0
p130 SenescentGSE19898 159395991 159396338 347 0
p130 SenescentGSE19898 159396433 159396585 152 0
p130 shRbQuiescentGSE19898 159395470 159396494 1024 0
p130 shRbSenescentGSE19898 159395838 159396417 579 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018