AutismKB 2.0

Annotation Detail for LAT


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Basic Information Top
Gene Symbol:LAT ( LAT1,pp36 )
Gene Full Name: linker for activation of T cells
Band: 16q13
Quick LinksEntrez ID:27040; OMIM: 602354; Uniprot ID:LAT_HUMAN; ENSEMBL ID: ENSG00000213658; HGNC ID: 18874
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
35Phosphoserine.
39Phosphothreonine.
40Phosphoserine.
41Phosphoserine.
43Phosphoserine.
84Phosphoserine.
101Phosphoserine.
106Phosphoserine.
109Phosphoserine.
110Phosphotyrosine (Probable).
156Phosphotyrosine (Probable).
161Phosphotyrosine (Probable).
200Phosphotyrosine.
220Phosphotyrosine (Probable).
224Phosphoserine.
240Phosphoserine.
241Phosphoserine.
255Phosphotyrosine.
Location(AA) Modifications Resource
26S-palmitoyl cysteine.Swiss-Prot 53.0
29S-palmitoyl cysteine.Swiss-Prot 53.0
38PhosphoserinePhospho.ELM 6.0
39PhosphothreoninePhospho.ELM 6.0
40PhosphoserinePhospho.ELM 6.0
84PhosphoserinePhospho.ELM 6.0
110Phosphotyrosine (Probable).Swiss-Prot 53.0
156Phosphotyrosine (Probable).Swiss-Prot 53.0
161Phosphotyrosine (Probable).Swiss-Prot 53.0
200Phosphotyrosine.Swiss-Prot 53.0
220PhosphotyrosinePhospho.ELM 6.0
220Phosphotyrosine (Probable).Swiss-Prot 53.0
224PhosphoserinePhospho.ELM 6.0
255Phosphotyrosine (Probable).Swiss-Prot 53.0
Location(AA) Modification Resource
26S-palmitoylHMM predict
39O-linkedHMM predict
41Phosphoserine(CK1)HMM predict
68O-linkedHMM predict
74Phosphoserine(ATM)HMM predict
84Phosphoserine(CDC2)HMM predict
94Phosphothreonine(CDC2)HMM predict
94Phosphothreonine(MAPK)HMM predict
94Phosphothreonine(CDK)HMM predict
96PhosphoserineHMM predict
101Phosphoserine(PKA)HMM predict
125C-linkedHMM predict
136Phosphothreonine(CDK)HMM predict
136Phosphothreonine(PKA)HMM predict
139O-linkedHMM predict
156Phosphotyrosine(Syk)HMM predict
156Phosphotyrosine(INSR)HMM predict
168O-linkedHMM predict
169O-linkedHMM predict
172O-linkedHMM predict
173O-linkedHMM predict
173O-linkedHMM predict
174O-linkedHMM predict
178O-linkedHMM predict
184Phosphothreonine(MAPK)HMM predict
193Phosphoserine(CK1)HMM predict
200SulfotyrosineHMM predict
206Phosphoserine(CK2)HMM predict
213Phosphoserine(IKK)HMM predict
220Phosphotyrosine(INSR)HMM predict
241Phosphoserine(ATM)HMM predict
255Phosphotyrosine(INSR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001014987
  • Location:chr16 28903887-28909596
  • strand:+
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Gata2 K562GSE18868 28927640 28928728 1088 18588
No data
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018