AutismKB 2.0

Annotation Detail for DAPP1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:DAPP1 ( BAM32,DKFZp667E0716 )
Gene Full Name: dual adaptor of phosphotyrosine and 3-phosphoinositides
Band: 4q23
Quick LinksEntrez ID:27071; OMIM: 605768; Uniprot ID:DAPP1_HUMAN; ENSEMBL ID: ENSG00000070190; HGNC ID: 16500
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
139Phosphotyrosine.
141Phosphoserine (By similarity).
Location(AA) Modifications Resource
139Phosphotyrosine (Lck)Phospho.ELM 6.0
Location(AA) Modification Resource
39N-linkedHMM predict
64N-linkedHMM predict
79Phosphoserine(PKG)HMM predict
87SulfotyrosineHMM predict
137Phosphoserine(CK1)HMM predict
139Phosphotyrosine(EGFR)HMM predict
139Phosphotyrosine(SRC)HMM predict
139Phosphotyrosine(Syk)HMM predict
153Phosphothreonine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014395
  • Location:chr4 100957012-101010333
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 100948464 100948835 371 8363
CTCF CD4SISSRdata 100948464 100948835 371 8363
CTCF JurkatGSE12889 100948407 100948740 333 8439
CTCF G2GSE9613 100948413 100948870 457 8371
CTCF G2GSE9613 100951707 100952306 599 5006
Oct1 HelaGSE14283 100948850 100948883 33 8146
Oct1 HelaGSE14283 100951652 100951683 31 5345
TFAP2C MCF7GSE21234 100956685 100957307 622 17
hScc1 BcellGSE12603 100948379 100948971 592 8338
hScc1 CdLSGSE12603 100948263 100949003 740 8380
hScc1 G2GSE9613 100948379 100949003 624 8322
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 101012872 101012911 39 2558
RNAII Tamoxifen-MCF7GSE14664 101012869 101012908 39 2555
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 100994845 100994986 141 0
CTCF G2GSE9613 100999901 101000090 189 0
FoxA1 MCF7MACSdata 101004128 101004290 162 0
Gata2 K562GSE18868 100982392 100983439 1047 0
Oct1 H2O2-HelaGSE14283 100959605 100959631 26 0
Oct1 H2O2-HelaGSE14283 100973662 100973689 27 0
Oct1 HelaGSE14283 100959257 100959291 34 0
Oct1 HelaGSE14283 100959583 100959632 49 0
Pol2 GM12878GSE19551 100956664 100957369 705 0
Rb shRbQuiescentGSE19898 100979709 100979948 239 0
hScc1 BcellGSE12603 100957094 100957700 606 0
hScc1 BcellGSE12603 100999805 101000016 211 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018