AutismKB 2.0

Annotation Detail for TJP3


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Basic Information Top
Gene Symbol:TJP3 ( MGC119546,ZO-3,ZO3 )
Gene Full Name: tight junction protein 3 (zona occludens 3)
Band: 19p13.3
Quick LinksEntrez ID:27134; OMIM: 612689; Uniprot ID:ZO3_HUMAN; ENSEMBL ID: ENSG00000105289; HGNC ID: 11829
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
112Phosphoserine (By similarity).
159Phosphoserine (By similarity).
164Phosphoserine.
169Phosphoserine (By similarity).
203Phosphoserine (By similarity).
579Phosphoserine (By similarity).
605Phosphoserine (By similarity).
919Phosphoserine.
920Phosphoserine.
Location(AA) Modifications Resource
159Phosphoserine (By similarity).Swiss-Prot 53.0
164Phosphoserine (By similarity).Swiss-Prot 53.0
169Phosphoserine (By similarity).Swiss-Prot 53.0
579Phosphoserine (By similarity).Swiss-Prot 53.0
919Phosphoserine (By similarity).Swiss-Prot 53.0
920Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
40O-linkedHMM predict
54Phosphothreonine(PKC)HMM predict
68N-linkedHMM predict
86N-linkedHMM predict
103Phosphoserine(CDC2)HMM predict
103PhosphoserineHMM predict
103Phosphoserine(IKK)HMM predict
106Phosphoserine(CDC2)HMM predict
112Phosphoserine(CK2)HMM predict
154MethylarginineHMM predict
159Phosphoserine(PKC)HMM predict
181MethyllysineHMM predict
251N-linkedHMM predict
265Phosphoserine(PKG)HMM predict
284O-linkedHMM predict
286Phosphoserine(ATM)HMM predict
288Phosphoserine(CK1)HMM predict
303Phosphoserine(MAPK)HMM predict
303Phosphoserine(ATM)HMM predict
316Phosphoserine(ATM)HMM predict
321O-linkedHMM predict
337Phosphoserine(ATM)HMM predict
341Phosphoserine(CDC2)HMM predict
341Phosphoserine(IKK)HMM predict
352Phosphoserine(PKC)HMM predict
352Phosphoserine(PKG)HMM predict
353Phosphoserine(PKB)HMM predict
353Phosphoserine(PKA)HMM predict
360Phosphoserine(CAMK2)HMM predict
360Phosphoserine(PKB)HMM predict
378Phosphotyrosine(Syk)HMM predict
383Phosphoserine(ATM)HMM predict
450N-linkedHMM predict
493Phosphotyrosine(EGFR)HMM predict
503Phosphoserine(ATM)HMM predict
555N-linkedHMM predict
579O-linkedHMM predict
601Phosphothreonine(PKC)HMM predict
602Phosphothreonine(PKC)HMM predict
668Phosphoserine(CDK)HMM predict
668Phosphoserine(CDC2)HMM predict
734Phosphoserine(PKA)HMM predict
735Phosphothreonine(PKA)HMM predict
735Phosphothreonine(PKC)HMM predict
760N-linkedHMM predict
819Phosphoserine(CK1)HMM predict
830Phosphotyrosine(INSR)HMM predict
836Phosphotyrosine(INSR)HMM predict
844Phosphotyrosine(Abl)HMM predict
868Phosphoserine(ATM)HMM predict
878Phosphoserine(PKG)HMM predict
919Phosphoserine(CK2)HMM predict
919Phosphoserine(CK2)HMM predict
919Phosphoserine(CK1)HMM predict
920Phosphoserine(CK1)HMM predict
920PhosphoserineHMM predict
925SulfotyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014428
  • Location:chr19 3679373-3701680
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 3670165 3670407 242 9088
CTCF CD4SISSRdata 3670165 3670407 242 9088
CTCF G2GSE9613 3670186 3670425 239 9068
Oct1 HelaGSE14283 3676698 3676747 49 2651
P300 T0-glioblastomaGSE21026 3672341 3672792 451 6807
P300 T30-glioblastomaGSE21026 3672034 3672951 917 6881
TFAP2C MCF7GSE21234 3673433 3674296 863 5509
TFAP2C MCF7GSE21234 3676895 3677346 451 2253
hScc1 BcellGSE12603 3671661 3671828 167 7629
hScc1 G2GSE9613 3670186 3670425 239 9068
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 3684913 3684957 44 0
ER MCF7GSE19013 3687326 3687743 417 0
ER MCF7GSE19013 3688021 3689235 1214 0
Fos K562GSE19551 3679527 3680022 495 0
Myc K562GSE19551 3679523 3679842 319 0
Nanog hESGSE18292 3694712 3694853 141 0
Oct1 H2O2-HelaGSE14283 3682041 3682098 57 0
Oct1 H2O2-HelaGSE14283 3688426 3688470 44 0
Oct1 HelaGSE14283 3682041 3682112 71 0
Oct1 HelaGSE14283 3688396 3688472 76 0
Oct1 HelaGSE14283 3694844 3694926 82 0
hScc1 BcellGSE12603 3697424 3697798 374 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
12500 mRNA TJP3 chr19 3686863 3701810 40 mRNA APBA3 chr19 3701770 3712673Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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