AutismKB 2.0

Annotation Detail for GPC3


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Basic Information Top
Gene Symbol:GPC3 ( DGSX,GTR2-2,MXR7,OCI-5,SDYS,SGB,SGBS,SGBS1 )
Gene Full Name: glypican 3
Band: Xq26.2
Quick LinksEntrez ID:2719; OMIM: 300037; Uniprot ID:GPC3_HUMAN; ENSEMBL ID: ENSG00000147257; HGNC ID: 4451
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
124N-linked (GlcNAc...) (Potential).
241N-linked (GlcNAc...) (Potential).
418N-linked (GlcNAc...) (Potential).
495O-linked (Xyl...) (heparan sulfate)
509O-linked (Xyl...) (heparan sulfate)
Location(AA) Modifications Resource
124N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
241N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
418N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
495O-linked (Xyl...) (heparan sulfate)(Potential).Swiss-Prot 53.0
509O-linked (Xyl...) (heparan sulfate)(Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
55Phosphothreonine(CDC2)HMM predict
55Phosphothreonine(CDK)HMM predict
124N-linkedHMM predict
127N-linkedHMM predict
134Phosphotyrosine(EGFR)HMM predict
138Phosphothreonine(MAPK)HMM predict
241N-linkedHMM predict
242Phosphothreonine(PKC)HMM predict
257Phosphothreonine(PKC)HMM predict
361Phosphotyrosine(Syk)HMM predict
362SulfotyrosineHMM predict
418N-linkedHMM predict
424N-linkedHMM predict
477Phosphoserine(PKB)HMM predict
539Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004484
  • Location:chrX 132497443-132947331
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 132948694 132949736 1042 1884
H3ac HepG2E 132948694 132949660 966 1846
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 132483915 132484195 280 13389
CTCF G2GSE9613 132492858 132493037 179 4496
Oct1 HelaGSE14283 132485710 132485782 72 11698
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 132687745 132688494 749 0
CTCF CD4GSE12889 132632225 132632347 122 0
CTCF CD4GSE12889 132660091 132660227 136 0
CTCF CD4GSE12889 132707233 132707408 175 0
CTCF CD4GSE12889 132737895 132738057 162 0
CTCF CD4GSE12889 132754165 132754472 307 0
CTCF CD4GSE12889 132800772 132801048 276 0
CTCF CD4SISSRdata 132632225 132632347 122 0
CTCF CD4SISSRdata 132660091 132660227 136 0
CTCF CD4SISSRdata 132707233 132707408 175 0
CTCF CD4SISSRdata 132737895 132738057 162 0
CTCF CD4SISSRdata 132754165 132754472 307 0
CTCF CD4SISSRdata 132800772 132801048 276 0
CTCF G2GSE9613 132499125 132499264 139 0
CTCF G2GSE9613 132632141 132632355 214 0
CTCF G2GSE9613 132737437 132738230 793 0
CTCF G2GSE9613 132753963 132754559 596 0
CTCF G2GSE9613 132800681 132800997 316 0
CTCF G2GSE9613 132883504 132883891 387 0
CTCF G2GSE9613 132946638 132947619 981 0
FOXA1 MCF7GSE15244 132589404 132590028 624 0
FOXA1 MCF7GSE15244 132637163 132638817 1654 0
FOXA1 MCF7GSE15244 132687844 132688612 768 0
FOXA1 MCF7GSE15244 132885361 132885568 207 0
FoxA1 MCF7MACSdata 132638187 132638490 303 0
H3ac HepG2E 132941048 132941789 741 0
H3ac HepG2E 132942587 132946801 4214 0
Nanog hESGSE18292 132896874 132897124 250 0
Oct1 H2O2-HelaGSE14283 132556724 132556753 29 0
Oct1 H2O2-HelaGSE14283 132591879 132591905 26 0
Oct1 H2O2-HelaGSE14283 132847807 132847838 31 0
Oct1 HelaGSE14283 132533475 132533508 33 0
Oct1 HelaGSE14283 132865859 132865916 57 0
P300 T30-glioblastomaGSE21026 132687668 132688560 892 0
PAX3-FKHR Rh4GSE19063 132841539 132843336 1797 0
RARA MCF7GSE15244 132637612 132638580 968 0
RARA MCF7GSE15244 132687844 132688274 430 0
RARA MCF7GSE15244 132885179 132885684 505 0
RARG MCF7GSE15244 132637198 132638609 1411 0
RARG MCF7GSE15244 132687914 132688310 396 0
RNAII Tamoxifen-MCF7GSE14664 132644941 132645013 72 0
hScc1 BcellGSE12603 132754096 132754488 392 0
hScc1 BcellGSE12603 132883504 132883755 251 0
hScc1 CdLSGSE12603 132631994 132632386 392 0
hScc1 CdLSGSE12603 132737913 132738230 317 0
hScc1 CdLSGSE12603 132753963 132754488 525 0
hScc1 CdLSGSE12603 132883469 132883855 386 0
hScc1 G2GSE9613 132499021 132499264 243 0
hScc1 G2GSE9613 132631562 132632472 910 0
hScc1 G2GSE9613 132737913 132738160 247 0
hScc1 G2GSE9613 132753843 132754559 716 0
hScc1 G2GSE9613 132800753 132801205 452 0
hScc1 G2GSE9613 132883469 132883855 386 0
p130 QuiescentGSE19898 132521600 132521822 222 0
p63 ME180GSE6132 132509051 132509313 262 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018