Annotation Detail for ARFIP1

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Basic Information Top

Gene Symbol:	ARFIP1 ( HSU52521,MGC117369 )
Gene Full Name:	ADP-ribosylation factor interacting protein 1
Band:	4q31.3
Quick Links	Entrez ID:27236; OMIM: 605928; Uniprot ID:ARFP1_HUMAN; ENSEMBL ID: ENSG00000164144; HGNC ID: 21496
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	153920169	153920837	668	59
p130	Senescent	GSE19898	153920114	153920786	672	112

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ER	E2-MCF7	GSE14664	154054040	154054074	34	1547
ER	Fulvestrant-MCF7	GSE14664	154054038	154054074	36	1546
Oct1	Hela	GSE14283	154054039	154054078	39	1548
P300	T30-glioblastoma	GSE21026	154065098	154065910	812	12994

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	CD4	GSE12889	153987289	153987615	326
CTCF	CD4	SISSRdata	153987289	153987615	326
ER	E2-MCF7	GSE14664	154050205	154050237	32
FoxA1	MCF7	MACSdata	153962950	153963257	307
GABP	k562	GSE8489	153920559	153921792	1233
H3K4me3	colorectal	cancer	153920606	153921792	1186
H3ac	HepG2	E	153920559	153921571	1012
Myc	hES	GSE17917	153987346	153987749	403
Nanog	ES	GSE20650	153990869	153991533	664
Nanog	hES	GSE18292	153991009	153991491	482
Oct1	H2O2-Hela	GSE14283	153935715	153935743	28
Oct1	Hela	GSE14283	153953462	153953494	32
Oct1	Hela	GSE14283	153965797	153965826	29
Oct1	Hela	GSE14283	153985651	153985678	27
Oct1	Hela	GSE14283	154011945	154011979	34
hScc1	Bcell	GSE12603	153920342	153920866	524
hScc1	Bcell	GSE12603	153987335	153987683	348
hScc1	CdLS	GSE12603	153987294	153987683	389
hScc1	G2	GSE9613	153987467	153987683	216

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7b	hsa-let-7b	22	18668040
hsa-let-7b*	hsa-let-7b	22	18668040
hsa-miR-1	hsa-mir-1-2	18	15685193
hsa-miR-1	hsa-mir-1-1	20	15685193
hsa-miR-1	hsa-mir-1-2	18	18668040
hsa-miR-1	hsa-mir-1-1	20	18668040
hsa-miR-124	hsa-mir-124-1	8	15685193
hsa-miR-124	hsa-mir-124-2	8	15685193
hsa-miR-124	hsa-mir-124-3	20	15685193
hsa-miR-155	hsa-mir-155	21	18668040
hsa-miR-155*	hsa-mir-155	21	18668040
hsa-miR-16	hsa-mir-16-1	13	18668040
hsa-miR-16	hsa-mir-16-2	3	18668040
hsa-miR-30a	hsa-mir-30a	6	18668040
hsa-miR-30a*	hsa-mir-30a	6	18668040
hsa-miR-30b	hsa-mir-30b	8	18668040
hsa-miR-30b*	hsa-mir-30b	8	18668040
hsa-miR-30c	hsa-mir-30c-2	6	18668040
hsa-miR-30c	hsa-mir-30c-1	1	18668040
hsa-miR-30c-1*	hsa-mir-30c-1	1	18668040
hsa-miR-30c-2*	hsa-mir-30c-2	6	18668040
hsa-miR-30d	hsa-mir-30d	8	18668040
hsa-miR-30d*	hsa-mir-30d	8	18668040
hsa-miR-30e	hsa-mir-30e	1	18668040
hsa-miR-30e*	hsa-mir-30e	1	18668040
hsa-miR-373	hsa-mir-373	19	15685193
hsa-miR-373*	hsa-mir-373	19	15685193

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
248	Unknown	MicroArray	miR-124	ARFIP1	n_a	15685193
935	Unknown	pSILAC	miR-155	ARFIP1	down 50-25%	18668040
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000164144		G1-to-S transition	n_a	n_a	"squamous cell, lymphocyte"	"benign tumour, malignant tumour, carcinoma, sarcoma"
ENSG00000164144		n_a	n_a	n_a	"squamous cell, lymphocyte"	"benign tumour, malignant tumour, carcinoma, sarcoma"

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
20339	mRNA	ARFIP1	chr4	154058727	154189053	170	EST		chr4	154049760	154058897	Non-exonic Bidirectional (NOB) pairs

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018