AutismKB 2.0

Annotation Detail for ARHGEF16


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Basic Information Top
Gene Symbol:ARHGEF16 ( GEF16,NBR )
Gene Full Name: Rho guanine nucleotide exchange factor (GEF) 16
Band: 1p36.32
Quick LinksEntrez ID:27237; OMIM: NA; Uniprot ID:ARHGG_HUMAN; ENSEMBL ID: ENSG00000130762; HGNC ID: 15515
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
6Phosphoserine (By similarity).
41Phosphoserine.
107Phosphoserine.
174Phosphoserine.
208Phosphoserine.
227Phosphoserine.
230Phosphoserine.
240Phosphoserine.
577Phosphoserine.
709PDZ-binding motif.
Location(AA) Modifications Resource
230Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
8Phosphoserine(CK2)HMM predict
9Phosphoserine(CK1)HMM predict
97O-linkedHMM predict
101Phosphothreonine(MAPK)HMM predict
101Phosphothreonine(CDC2)HMM predict
185Phosphoserine(ATM)HMM predict
185Phosphoserine(CK1)HMM predict
191Phosphoserine(CDC2)HMM predict
216Phosphotyrosine(Syk)HMM predict
225N-linkedHMM predict
227Phosphoserine(ATM)HMM predict
230Phosphoserine(CK2)HMM predict
239Phosphoserine(CK1)HMM predict
240Phosphoserine(CDC2)HMM predict
240Phosphoserine(CDK)HMM predict
240Phosphoserine(CK1)HMM predict
280Phosphothreonine(PKC)HMM predict
383Phosphotyrosine(Syk)HMM predict
383Phosphotyrosine(SRC)HMM predict
546Phosphotyrosine(Syk)HMM predict
546Phosphotyrosine(SRC)HMM predict
546Phosphotyrosine(INSR)HMM predict
574N-linkedHMM predict
576O-linkedHMM predict
578Phosphoserine(ATM)HMM predict
578Phosphoserine(CK1)HMM predict
578Phosphoserine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014448
  • Location:chr1 3369981-3387534
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 3359532 3359852 320 10290
CTCF CD4SISSRdata 3359532 3359852 320 10290
CTCF G2GSE9613 3358674 3359268 594 11011
CTCF G2GSE9613 3359721 3360120 399 10061
CTCF G2GSE9613 3360578 3361265 687 9060
CTCF G2GSE9613 3363240 3363621 381 6551
CTCF G2GSE9613 3364013 3364745 732 5603
H3ac HepG2E 3365596 3366605 1009 3881
Oct1 HelaGSE14283 3357736 3357768 32 12230
Oct1 HelaGSE14283 3358974 3359010 36 10990
TFAP2C MCF7GSE21234 3359500 3360062 562 10201
TFAP2C MCF7GSE21234 3363034 3363842 808 6544
TFAP2C MCF7GSE21234 3365945 3367073 1128 3473
hScc1 BcellGSE12603 3358783 3359174 391 11003
hScc1 BcellGSE12603 3359688 3361616 1928 9330
hScc1 BcellGSE12603 3368972 3369668 696 662
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 3390406 3390554 148 2946
CTCF CD4SISSRdata 3390406 3390554 148 2946
CTCF G2GSE9613 3388803 3390563 1760 2149
TFAP2C MCF7GSE21234 3388350 3389102 752 1192
hScc1 BcellGSE12603 3388224 3389148 924 1152
hScc1 BcellGSE12603 3390078 3390563 485 2786
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 3370231 3371751 1520 0
CTCF G2GSE9613 3372204 3372502 298 0
CTCF G2GSE9613 3374564 3375985 1421 0
CTCF G2GSE9613 3379842 3379974 132 0
CTCF G2GSE9613 3381057 3381304 247 0
CTCF G2GSE9613 3382269 3383039 770 0
CTCF G2GSE9613 3386708 3387370 662 0
TFAP2C MCF7GSE21234 3370970 3371379 409 0
TFAP2C MCF7GSE21234 3377729 3378592 863 0
hScc1 BcellGSE12603 3375308 3375706 398 0
hScc1 BcellGSE12603 3382269 3382651 382 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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