AutismKB 2.0

Annotation Detail for LSM3


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Basic Information Top
Gene Symbol:LSM3 ( SMX4,USS2,YLR438C )
Gene Full Name: LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Band: 3p25.1
Quick LinksEntrez ID:27258; OMIM: 607283; Uniprot ID:LSM3_HUMAN; ENSEMBL ID: ENSG00000170860; HGNC ID: 17874
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
Location(AA) Modifications Resource
2N-acetylalanine.Swiss-Prot 53.0
Location(AA) Modification Resource
30Phosphotyrosine(EGFR)HMM predict
30Phosphotyrosine(INSR)HMM predict
71Phosphotyrosine(EGFR)HMM predict
71Phosphotyrosine(INSR)HMM predict
71Phosphotyrosine(SRC)HMM predict
71Phosphotyrosine(Syk)HMM predict
75Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014463
  • Location:chr3 14195340-14214839
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 14195116 14195562 446 2
Nanog ESGSE20650 14195106 14195412 306 82
p130 QuiescentGSE19898 14194904 14195595 691 91
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 14220033 14220271 238 5313
CTCF CD4SISSRdata 14220033 14220271 238 5313
CTCF G2GSE9613 14220142 14220508 366 5486
CTCF G2GSE9613 14226453 14226769 316 11772
CTCF G2GSE9613 14229211 14229576 365 14554
ER MCF7GSE19013 14218615 14219374 759 4155
FOXA1 MCF7GSE15244 14220105 14221493 1388 5960
Gata2 K562GSE18868 14221036 14221871 835 6614
RARA MCF7GSE15244 14218164 14221752 3588 5119
RARG MCF7GSE15244 14218124 14221717 3593 5081
USF1 HepG2E 14233001 14233208 207 18265
USF2 HepG2E 14233001 14233208 207 18265
hScc1 BcellGSE12603 14219424 14220579 1155 5162
hScc1 CdLSGSE12603 14219822 14220471 649 5307
hScc1 CdLSGSE12603 14220850 14221180 330 6176
hScc1 G2GSE9613 14219900 14220543 643 5382
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
E2F4 G0GSE7516 14195050 14195634 584 0
H3K4me3 colorectalcancer 14195597 14196035 438 0
H3ac HepG2E 14195159 14196752 1593 0
LIN9 G0GSE7516 14195050 14195896 846 0
LIN9 SGSE7516 14195050 14195932 882 0
TAF k562GSE8489 14195222 14196752 1530 0
TAFII hESGSE17917 14195044 14195679 635 0
p130 shRbSenescentGSE19898 14195198 14195703 505 0
p130 G0GSE7516 14195012 14195710 698 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018