Annotation Detail for APEX2
Basic Information Top
| Gene Symbol: | APEX2 ( APE2,APEXL2,XTH2 ) |
|---|---|
| Gene Full Name: | APEX nuclease (apurinic/apyrimidinic endonuclease) 2 |
| Band: | Xp11.21 |
| Quick Links | Entrez ID:27301; OMIM: 300773; Uniprot ID:APEX2_HUMAN; ENSEMBL ID: ENSG00000169188; HGNC ID: 17889 |
| Relate to Another Database: | SFARIGene; denovo-db |
| No data |
| No data |
| Location(AA) | Modification | Resource |
|---|---|---|
| 52 | Phosphothreonine(PKA) | HMM predict |
| 71 | Phosphoserine(CDK) | HMM predict |
| 75 | N-linked | HMM predict |
| 89 | N-linked | HMM predict |
| 113 | Phosphotyrosine(INSR) | HMM predict |
| 278 | Phosphotyrosine(INSR) | HMM predict |
| 361 | N-linked | HMM predict |
| 382 | O-linked | HMM predict |
| 400 | O-linked | HMM predict |
| 423 | Phosphothreonine(CDK) | HMM predict |
| 426 | Phosphothreonine(CDC2) | HMM predict |
| 426 | Phosphothreonine(MAPK) | HMM predict |
| 426 | Phosphothreonine(CDK) | HMM predict |
| 442 | Phosphothreonine(PKC) | HMM predict |
| 480 | Phosphothreonine | HMM predict |
| 502 | Proline | HMM predict |
- RefSeq ID: NM_014481
- Location:chrX 55043504-55050935
- strand:+
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| ETS1 | Jurkat | GSE17954 | 55042738 | 55043923 | 1185 | 174 |
| NRSF | Jurkat | SISSRdata | 55043404 | 55043579 | 175 | 13 |
| PHF8 | 293T | GSE20725 | 55042835 | 55044026 | 1191 | 74 |
| PHF8 | HeLa | GSE20725 | 55042674 | 55044108 | 1434 | 114 |
| Pol2 | GM12878 | GSE19551 | 55042698 | 55043870 | 1172 | 221 |
| Rb | Quiescent | GSE19898 | 55043185 | 55043554 | 369 | 135 |
| Rb | Senescent | GSE19898 | 55043018 | 55043711 | 693 | 140 |
| Rb | shRbSenescence | GSE19898 | 55043333 | 55043578 | 245 | 49 |
| TFAP2C | MCF7 | GSE21234 | 55042936 | 55043709 | 773 | 182 |
| hScc1 | G2 | GSE9613 | 55042771 | 55043131 | 360 | 554 |
| p130 | Senescent | GSE19898 | 55043187 | 55043697 | 510 | 63 |
| p130 | shRbQuiescent | GSE19898 | 55043197 | 55043687 | 490 | 63 |
| p130 | shRbSenescent | GSE19898 | 55043161 | 55043759 | 598 | 45 |
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | G2 | GSE9613 | 55049735 | 55050605 | 870 | 0 |
| H3ac | HepG2 | E | 55042701 | 55044943 | 2242 | 0 |
| Nanog | ES | GSE20650 | 55043276 | 55043736 | 460 | 0 |
| Micro RNA Name | Stem Loop Name | The chromosome that miRNA located | Publication |
|---|---|---|---|
| hsa-miR-1 | hsa-mir-1-2 | 18 | 15685193 |
| hsa-miR-1 | hsa-mir-1-1 | 20 | 15685193 |
| hsa-miR-124 | hsa-mir-124-1 | 8 | 15685193 |
| hsa-miR-124 | hsa-mir-124-2 | 8 | 15685193 |
| hsa-miR-124 | hsa-mir-124-3 | 20 | 15685193 |
| hsa-miR-373 | hsa-mir-373 | 19 | 15685193 |
| hsa-miR-373* | hsa-mir-373 | 19 | 15685193 |
| ID in Tarbase | Data Type | Support Type | miRNA | Gene | Direct Support | Publication |
|---|---|---|---|---|---|---|
| 256 | Unknown | MicroArray | miR-124 | APEX2 | n_a | 15685193 |
| Ensembl | Protein Type | Differentially expressed in | Pathology or Event | Mis Regulation | Gene Expression | Tumour Involvement |
| ENSG00000169188 | G1-to-S transition | n_a | n_a | n_a | n_a |
Cis-Nats regulation