AutismKB 2.0

Annotation Detail for KCNMB4


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Basic Information Top
Gene Symbol:KCNMB4 ( - )
Gene Full Name: potassium large conductance calcium-activated channel, subfamily M, beta member 4
Band: 12q15
Quick LinksEntrez ID:27345; OMIM: 605223; Uniprot ID:KCMB4_HUMAN; ENSEMBL ID: ENSG00000135643; HGNC ID: 6289
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
53N-linked (GlcNAc...).
90N-linked (GlcNAc...).
Location(AA) Modifications Resource
11PhosphothreoninePhospho.ELM 6.0
17PhosphoserinePhospho.ELM 6.0
53N-linked (GlcNAc...).Swiss-Prot 53.0
90N-linked (GlcNAc...).Swiss-Prot 53.0
210PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
38S-palmitoylHMM predict
41Phosphoserine(MAPK)HMM predict
53N-linkedHMM predict
90N-linkedHMM predict
91N-linkedHMM predict
95N-linkedHMM predict
102Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014505
  • Location:chr12 69046328-69111243
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
LIN9 G0GSE7516 69045228 69046093 865 668
Oct4 ESGSE20650 69040727 69040968 241 5481
TFAP2C MCF7GSE21234 69046023 69046559 536 38
hScc1 G2GSE9613 69046127 69046519 392 6
p130 QuiescentGSE19898 69045856 69046228 372 287
p130 SenescentGSE19898 69045815 69046208 393 317
p130 shRbQuiescentGSE19898 69045699 69046170 471 394
p130 shRbSenescentGSE19898 69045561 69046231 670 433
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 69125083 69125299 216 13948
CTCF G2GSE9613 69127655 69127800 145 16484
ER E2-MCF7GSE14664 69125093 69125125 32 13866
ER E2-MCF7GSE14664 69127111 69127143 32 15884
FOXA1 DLD1GSE12801 69124943 69125299 356 13878
FOXA1 DLD1GSE12801 69129461 69130125 664 18550
FOXA1 MCF7GSE15244 69124943 69125083 140 13770
VDR GM10861-stimGSE22484 69124796 69125644 848 13977
hScc1 G2GSE9613 69125083 69125299 216 13948
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 69046163 69046519 356 0
CTCF G2GSE9613 69046935 69047319 384 0
FOXA1 DLD1GSE12801 69080190 69080708 518 0
GATA3 MCF7GSE15244 69098137 69098787 650 0
Oct1 H2O2-HelaGSE14283 69084807 69084848 41 0
Oct1 H2O2-HelaGSE14283 69088063 69088090 27 0
Oct1 H2O2-HelaGSE14283 69110208 69110255 47 0
Oct1 HelaGSE14283 69084809 69084849 40 0
Oct1 HelaGSE14283 69092022 69092087 65 0
Oct1 HelaGSE14283 69110213 69110258 45 0
TFAP2C MCF7GSE21234 69046675 69047626 951 0
hScc1 BcellGSE12603 69046367 69047319 952 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018