AutismKB 2.0

Annotation Detail for STK39


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Basic Information Top
Gene Symbol:STK39 ( DCHT,DKFZp686K05124,PASK,SPAK )
Gene Full Name: serine threonine kinase 39
Band: 2q24.3
Quick LinksEntrez ID:27347; OMIM: 607648; Uniprot ID:STK39_HUMAN; ENSEMBL ID: ENSG00000198648; HGNC ID: 17717
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
349N6-acetyllysine.
354Phosphothreonine.
366Nuclear localization signal (Potential).
370Phosphoserine.
371Phosphoserine.
385Phosphoserine.
391Caspase cleavage related site.
Location(AA) Modifications Resource
233Phosphothreonine (Wnk1)Phospho.ELM 6.0
311Phosphoserine (PKC theta)Phospho.ELM 6.0
325Phosphoserine (PKC theta)Phospho.ELM 6.0
356Phosphothreonine.Swiss-Prot 53.0
372Phosphoserine.Swiss-Prot 53.0
373Phosphoserine (Wnk1)Phospho.ELM 6.0
Location(AA) Modification Resource
7PhosphoserineHMM predict
7Phosphoserine(CDC2)HMM predict
32O-linkedHMM predict
116Phosphoserine(IKK)HMM predict
125O-linkedHMM predict
325Phosphoserine(PKC)HMM predict
325PhosphoserineHMM predict
403Phosphoserine(ATM)HMM predict
436Phosphoserine(ATM)HMM predict
446Phosphotyrosine(EGFR)HMM predict
446Phosphotyrosine(Syk)HMM predict
450Phosphoserine(PKB)HMM predict
463Phosphoserine(PKG)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_013233
  • Location:chr2 168518776-168812350
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 168812151 168812982 831 216
CTCF G2GSE9613 168820506 168820836 330 8321
Oct1 H2O2-HelaGSE14283 168827007 168827036 29 14671
TFAP2C MCF7GSE21234 168819295 168819799 504 7197
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog ESGSE20650 168511121 168511723 602 7355
Oct1 HelaGSE14283 168515166 168515203 37 3592
TAF k562GSE8489 168504929 168505762 833 13431
TAF k562GSE8489 168506130 168507030 900 12197
TFAP2C MCF7GSE21234 168518447 168518893 446 107
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 168577974 168578978 1004 0
CTCF CD4GSE12889 168701146 168701402 256 0
CTCF CD4SISSRdata 168701146 168701402 256 0
CTCF G2GSE9613 168651889 168652054 165 0
CTCF G2GSE9613 168683394 168683956 562 0
CTCF G2GSE9613 168725493 168725942 449 0
CTCF G2GSE9613 168811049 168811771 722 0
ER Fulvestrant-MCF7GSE14664 168524095 168524127 32 0
ER Fulvestrant-MCF7GSE14664 168563421 168563478 57 0
ER Fulvestrant-MCF7GSE14664 168606751 168606786 35 0
ER MCF7GSE19013 168620895 168621377 482 0
H3K4me2 HCT116GSE10453 168809892 168810466 574 0
Nanog hESGSE18292 168628950 168629283 333 0
Oct1 H2O2-HelaGSE14283 168614675 168614708 33 0
Oct1 H2O2-HelaGSE14283 168671183 168671214 31 0
Oct1 H2O2-HelaGSE14283 168719997 168720025 28 0
Oct1 HelaGSE14283 168524097 168524129 32 0
Oct1 HelaGSE14283 168587220 168587260 40 0
Oct1 HelaGSE14283 168603785 168603825 40 0
Oct1 HelaGSE14283 168606755 168606783 28 0
Oct1 HelaGSE14283 168614675 168614707 32 0
Oct1 HelaGSE14283 168624904 168624943 39 0
Oct1 HelaGSE14283 168659467 168659499 32 0
Oct1 HelaGSE14283 168739765 168739792 27 0
Oct1 HelaGSE14283 168777403 168777436 33 0
Oct1 HelaGSE14283 168811274 168811309 35 0
P300 T30-glioblastomaGSE21026 168775755 168776581 826 0
PHF8 HeLaGSE20725 168810886 168812980 2094 0
RARA MCF7GSE15244 168775759 168777150 1391 0
RNAII Tamoxifen-MCF7GSE14664 168587225 168587263 38 0
TAF k562GSE8489 168529124 168530229 1105 0
TFAP2C MCF7GSE21234 168720410 168720850 440 0
VDR GM10861-stimGSE22484 168648830 168649868 1038 0
hScc1 BcellGSE12603 168658350 168658648 298 0
hScc1 BcellGSE12603 168683256 168684362 1106 0
hScc1 BcellGSE12603 168710047 168710465 418 0
hScc1 BcellGSE12603 168811049 168811401 352 0
hScc1 CdLSGSE12603 168683256 168684473 1217 0
hScc1 G2GSE9613 168683475 168683893 418 0
hScc1 G2GSE9613 168811146 168811771 625 0
p130 SenescentGSE19898 168754713 168754904 191 0
p63 keratinocytesGSE17611 168598345 168599374 1029 0
p63 keratinocytesGSE17611 168662060 168662878 818 0
p63 keratinocytesGSE17611 168775621 168776566 945 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-34a hsa-mir-34a 1 18497571
hsa-miR-34a hsa-mir-34a 1 18497571
hsa-miR-34a* hsa-mir-34a 1 18497571
hsa-miR-34a* hsa-mir-34a 1 18497571
hsa-miR-34b hsa-mir-34b 11 18497571
hsa-miR-34b hsa-mir-34b 11 18497571
hsa-miR-34b* hsa-mir-34b 11 18497571
hsa-miR-34b* hsa-mir-34b 11 18497571
hsa-miR-34c-3p hsa-mir-34c 11 18497571
hsa-miR-34c-3p hsa-mir-34c 11 18497571
hsa-miR-34c-5p hsa-mir-34c 11 18497571
hsa-miR-34c-5p hsa-mir-34c 11 18497571
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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