AutismKB 2.0

Annotation Detail for GLI2


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Basic Information Top
Gene Symbol:GLI2 ( HPE9,THP1,THP2 )
Gene Full Name: GLI family zinc finger 2
Band: 2q14.2
Quick LinksEntrez ID:2736; OMIM: 165230; Uniprot ID:GLI2_HUMAN; ENSEMBL ID: ENSG00000074047; HGNC ID: 4318
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
725Phosphothreonine (By similarity).
Location(AA) Modifications Resource
Location(AA) Modification Resource
7N-linkedHMM predict
17Phosphoserine(IKK)HMM predict
21Phosphoserine(CK1)HMM predict
36O-linkedHMM predict
47PhosphoserineHMM predict
60Phosphoserine(MAPK)HMM predict
81Phosphoserine(CDC2)HMM predict
144S-palmitoylHMM predict
205Phosphotyrosine(Jak)HMM predict
227N-linkedHMM predict
232N-linkedHMM predict
248Phosphothreonine(PKA)HMM predict
279Phosphothreonine(CDK)HMM predict
279Phosphothreonine(MAPK)HMM predict
303O-linkedHMM predict
306O-linkedHMM predict
306Phosphoserine(ATM)HMM predict
334Phosphoserine(IKK)HMM predict
338Phosphoserine(CK1)HMM predict
338Phosphoserine(IKK)HMM predict
341O-linkedHMM predict
341Phosphoserine(IKK)HMM predict
341Phosphoserine(CDC2)HMM predict
349N-linkedHMM predict
396Phosphothreonine(PKC)HMM predict
396Phosphothreonine(PKA)HMM predict
422Phosphothreonine(CDK)HMM predict
422Phosphothreonine(MAPK)HMM predict
438Phosphoserine(IKK)HMM predict
442N-linkedHMM predict
464Phosphoserine(CK1)HMM predict
466Phosphoserine(IKK)HMM predict
480Phosphoserine(CK1)HMM predict
480Phosphoserine(PKA)HMM predict
480Phosphoserine(IKK)HMM predict
480Phosphoserine(PKG)HMM predict
481Phosphoserine(IKK)HMM predict
483Phosphoserine(CK1)HMM predict
483O-linkedHMM predict
484O-linkedHMM predict
496Phosphoserine(PKG)HMM predict
496PhosphoserineHMM predict
499Phosphoserine(CDC2)HMM predict
503Phosphoserine(CDK)HMM predict
503Phosphoserine(CDC2)HMM predict
504Phosphoserine(CDK)HMM predict
507Phosphoserine(CK1)HMM predict
507Phosphoserine(CK2)HMM predict
508Phosphoserine(CAMK2)HMM predict
508Phosphoserine(IKK)HMM predict
508Phosphoserine(PKA)HMM predict
508Phosphoserine(PKG)HMM predict
511Phosphoserine(CDC2)HMM predict
520N-linkedHMM predict
527Phosphotyrosine(INSR)HMM predict
538Phosphoserine(CK1)HMM predict
539Phosphoserine(PKG)HMM predict
539Phosphoserine(CK1)HMM predict
539Phosphoserine(CAMK2)HMM predict
539Phosphoserine(CK2)HMM predict
539Phosphoserine(IKK)HMM predict
539Phosphoserine(PKA)HMM predict
542Phosphoserine(IKK)HMM predict
552N-linkedHMM predict
575Phosphothreonine(MAPK)HMM predict
575O-linkedHMM predict
575O-linkedHMM predict
638Phosphothreonine(PKC)HMM predict
642Phosphoserine(PKB)HMM predict
642PhosphoserineHMM predict
642Phosphoserine(PKA)HMM predict
642Phosphoserine(PKG)HMM predict
642Phosphoserine(PKC)HMM predict
652Phosphoserine(CK1)HMM predict
697Phosphoserine(CDK)HMM predict
697Phosphoserine(CDC2)HMM predict
697O-linkedHMM predict
702Phosphoserine(IKK)HMM predict
825Phosphothreonine(PKC)HMM predict
881O-linkedHMM predict
885Phosphoserine(ATM)HMM predict
904Phosphoserine(IKK)HMM predict
958Phosphothreonine(PKC)HMM predict
1009Phosphotyrosine(Syk)HMM predict
1050Phosphoserine(CDC2)HMM predict
1052Phosphothreonine(PKC)HMM predict
1081Phosphoserine(ATM)HMM predict
1098O-linkedHMM predict
1143Phosphoserine(ATM)HMM predict
1162Phosphoserine(CDC2)HMM predict
1162Phosphoserine(MAPK)HMM predict
1162O-linkedHMM predict
1208Phosphoserine(CK1)HMM predict
1208Phosphoserine(IKK)HMM predict
1210Phosphoserine(ATM)HMM predict
1212N-linkedHMM predict
1218Phosphothreonine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005270
  • Location:chr2 121266326-121466320
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 121250892 121251074 182 15344
CTCF G2GSE9613 121251613 121251976 363 14532
CTCF G2GSE9613 121252343 121252655 312 13828
CTCF G2GSE9613 121259085 121259709 624 6930
CTCF G2GSE9613 121263719 121264095 376 2420
Nanog hESGSE18292 121260327 121260883 556 5722
Oct1 H2O2-HelaGSE14283 121263816 121263850 34 2494
Oct1 HelaGSE14283 121263816 121263850 34 2494
Oct4 hESGSE21916 121260125 121261099 974 5715
Sox2 hESGSE18292 121260558 121261085 527 5505
hScc1 BcellGSE12603 121259050 121259544 494 7030
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 121482981 121483302 321 16821
ER Fulvestrant-MCF7GSE14664 121470733 121470779 46 4436
Oct1 HelaGSE14283 121470734 121470786 52 4440
Oct1 HelaGSE14283 121472641 121472670 29 6335
Oct1 HelaGSE14283 121482018 121482047 29 15712
Oct1 HelaGSE14283 121482609 121482646 37 16307
TAF HelaGSE8489 121480569 121481012 443 14470
TFAP2C MCF7GSE21234 121478924 121479451 527 12867
hScc1 BcellGSE12603 121483054 121483302 248 16858
hScc1 G2GSE9613 121482981 121483302 321 16821
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 121388671 121389915 1244 0
CBP T30-glioblastomaGSE21026 121408473 121409425 952 0
CTCF G2GSE9613 121268399 121268803 404 0
CTCF G2GSE9613 121271459 121271650 191 0
CTCF G2GSE9613 121277561 121277949 388 0
CTCF G2GSE9613 121284340 121284709 369 0
CTCF G2GSE9613 121285228 121285557 329 0
CTCF G2GSE9613 121294515 121294648 133 0
CTCF G2GSE9613 121296058 121296558 500 0
CTCF G2GSE9613 121298480 121298834 354 0
CTCF G2GSE9613 121299448 121299627 179 0
CTCF G2GSE9613 121300082 121300414 332 0
CTCF G2GSE9613 121304445 121304811 366 0
CTCF G2GSE9613 121325422 121325654 232 0
CTCF G2GSE9613 121328683 121328995 312 0
CTCF G2GSE9613 121335016 121335502 486 0
CTCF G2GSE9613 121336395 121336731 336 0
CTCF G2GSE9613 121337871 121338330 459 0
CTCF G2GSE9613 121341282 121342211 929 0
CTCF G2GSE9613 121349391 121349708 317 0
CTCF G2GSE9613 121350806 121351160 354 0
CTCF G2GSE9613 121356145 121356472 327 0
CTCF G2GSE9613 121360613 121361085 472 0
CTCF G2GSE9613 121361584 121361840 256 0
CTCF G2GSE9613 121373584 121373950 366 0
CTCF G2GSE9613 121379410 121379792 382 0
CTCF G2GSE9613 121380445 121382266 1821 0
CTCF G2GSE9613 121384927 121385416 489 0
CTCF G2GSE9613 121385815 121386113 298 0
CTCF G2GSE9613 121388437 121389363 926 0
CTCF G2GSE9613 121391837 121392015 178 0
CTCF G2GSE9613 121393550 121394182 632 0
CTCF G2GSE9613 121396520 121397073 553 0
CTCF G2GSE9613 121400850 121401143 293 0
CTCF G2GSE9613 121405913 121406245 332 0
CTCF G2GSE9613 121412766 121413002 236 0
CTCF G2GSE9613 121417107 121417350 243 0
CTCF G2GSE9613 121422180 121422739 559 0
CTCF G2GSE9613 121423461 121423977 516 0
CTCF G2GSE9613 121426647 121427060 413 0
CTCF G2GSE9613 121427635 121428408 773 0
CTCF G2GSE9613 121428961 121430089 1128 0
CTCF G2GSE9613 121430525 121433164 2639 0
CTCF G2GSE9613 121439352 121439702 350 0
CTCF G2GSE9613 121442710 121442932 222 0
CTCF G2GSE9613 121443984 121444272 288 0
CTCF G2GSE9613 121445955 121446978 1023 0
CTCF G2GSE9613 121448727 121449170 443 0
CTCF G2GSE9613 121450680 121451032 352 0
CTCF G2GSE9613 121456812 121457122 310 0
CTCF G2GSE9613 121457433 121457766 333 0
CTCF G2GSE9613 121458169 121458933 764 0
CTCF G2GSE9613 121460174 121461306 1132 0
CTCF G2GSE9613 121462126 121464490 2364 0
ER E2-MCF7GSE14664 121425689 121425722 33 0
ER Fulvestrant-MCF7GSE14664 121351196 121351228 32 0
ER MCF7GSE19013 121407587 121408506 919 0
FOXA1 MCF7GSE15244 121408585 121409781 1196 0
FoxA1 MCF7MACSdata 121408953 121409326 373 0
Oct1 H2O2-HelaGSE14283 121284338 121284365 27 0
Oct1 H2O2-HelaGSE14283 121298461 121298488 27 0
Oct1 H2O2-HelaGSE14283 121345545 121345586 41 0
Oct1 H2O2-HelaGSE14283 121352956 121352988 32 0
Oct1 H2O2-HelaGSE14283 121435798 121435829 31 0
Oct1 HelaGSE14283 121266545 121266604 59 0
Oct1 HelaGSE14283 121295799 121295828 29 0
Oct1 HelaGSE14283 121316949 121317027 78 0
Oct1 HelaGSE14283 121337770 121337799 29 0
Oct1 HelaGSE14283 121345170 121345205 35 0
Oct1 HelaGSE14283 121345549 121345586 37 0
Oct1 HelaGSE14283 121352956 121353024 68 0
Oct1 HelaGSE14283 121368404 121368443 39 0
Oct1 HelaGSE14283 121420230 121420269 39 0
Oct1 HelaGSE14283 121427530 121427561 31 0
Oct1 HelaGSE14283 121435795 121435835 40 0
Oct1 HelaGSE14283 121457183 121457211 28 0
P300 T0-glioblastomaGSE21026 121400522 121400919 397 0
P300 T30-glioblastomaGSE21026 121292520 121293283 763 0
P300 T30-glioblastomaGSE21026 121388492 121389895 1403 0
P300 T30-glioblastomaGSE21026 121408569 121410136 1567 0
Rb QuiescentGSE19898 121294372 121294822 450 0
TFAP2C MCF7GSE21234 121370821 121371381 560 0
TFAP2C MCF7GSE21234 121393945 121394588 643 0
TFAP2C MCF7GSE21234 121410659 121411268 609 0
TFAP2C MCF7GSE21234 121463311 121463739 428 0
hScc1 BcellGSE12603 121344364 121344858 494 0
hScc1 BcellGSE12603 121410956 121411165 209 0
hScc1 BcellGSE12603 121427999 121428150 151 0
hScc1 BcellGSE12603 121428961 121429319 358 0
hScc1 BcellGSE12603 121462126 121463075 949 0
hScc1 BcellGSE12603 121463734 121464080 346 0
hScc1 G2GSE9613 121423530 121423977 447 0
hScc1 G2GSE9613 121431989 121433009 1020 0
hScc1 G2GSE9613 121462126 121463433 1307 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-141 hsa-mir-141 12 18698484
hsa-miR-141* hsa-mir-141 12 18698484
hsa-miR-155 hsa-mir-155 21 19386588
hsa-miR-155* hsa-mir-155 21 19386588
hsa-miR-200a hsa-mir-200a 1 18698484
hsa-miR-200a* hsa-mir-200a 1 18698484
hsa-miR-200b hsa-mir-200b 1 18698484
hsa-miR-200b* hsa-mir-200b 1 18698484
hsa-miR-200c hsa-mir-200c 12 18698484
hsa-miR-200c* hsa-mir-200c 12 18698484
hsa-miR-205 hsa-mir-205 1 18698484
hsa-miR-429 hsa-mir-429 1 18698484
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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