AutismKB 2.0

Annotation Detail for GLS


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Basic Information Top
Gene Symbol:GLS ( AAD20,DKFZp686O15119,FLJ10358,GLS1,KIAA0838 )
Gene Full Name: glutaminase
Band: 2q32.2
Quick LinksEntrez ID:2744; OMIM: 138280; Uniprot ID:GLSK_HUMAN; ENSEMBL ID: ENSG00000115419; HGNC ID: 4331
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
311N6-acetyllysine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
17Phosphoserine(CDC2)HMM predict
24Phosphothreonine(PKC)HMM predict
39MethylarginineHMM predict
73PhosphoserineHMM predict
75Phosphoserine(CDC2)HMM predict
75Phosphoserine(ATM)HMM predict
77Phosphoserine(CK1)HMM predict
95O-linkedHMM predict
106O-linkedHMM predict
126Phosphoserine(CK2)HMM predict
226Phosphoserine(IKK)HMM predict
375N-linkedHMM predict
384Phosphoserine(CK1)HMM predict
449Phosphoserine(MAPK)HMM predict
530Phosphotyrosine(INSR)HMM predict
553Phosphoserine(PKA)HMM predict
584Phosphotyrosine(Syk)HMM predict
620N-linkedHMM predict
621N-linkedHMM predict
658N-linkedHMM predict
664N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014905
  • Location:chr2 191453846-191538509
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 191452947 191454046 1099 350
Nanog hESGSE18292 191433804 191434274 470 19808
PHF8 293TGSE20725 191453136 191454317 1181 120
Pol2 GM12878GSE19551 191453043 191454176 1133 237
Rb GrowingGSE19898 191453326 191453558 232 405
Rb GrowingGSE19898 191453719 191453939 220 18
hScc1 BcellGSE12603 191453123 191454144 1021 213
p130 QuiescentGSE19898 191453667 191453804 137 111
p130 shRbQuiescentGSE19898 191453198 191453979 781 258
p130 shRbSenescentGSE19898 191453504 191453863 359 163
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 191521034 191521166 132 0
CTCF CD4SISSRdata 191521034 191521166 132 0
CTCF G2GSE9613 191453553 191454719 1166 0
CTCF G2GSE9613 191523764 191523982 218 0
H3K4me3 colorectalcancer 191455125 191455819 694 0
H3ac HepG2E 191455089 191457352 2263 0
Pol2 GM12878GSE19551 191534774 191535677 903 0
PolII HeLaGSE12783 191452966 191456102 3136 0
Rb SenescentGSE19898 191454770 191454922 152 0
TAF k562GSE8489 191454978 191456453 1475 0
TFAP2C MCF7GSE21234 191453663 191454029 366 0
USF1 HepG2E 191455014 191456029 1015 0
hScc1 BcellGSE12603 191520893 191521264 371 0
hScc1 CdLSGSE12603 191520621 191521264 643 0
p130 QuiescentGSE19898 191454837 191455086 249 0
p130 shRbQuiescentGSE19898 191454752 191455254 502 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
15417 mRNA GLS chr2 191571102 191655771 332 EST chr2 191654594 191665167Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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