AutismKB 2.0

Annotation Detail for GLUD1


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Basic Information Top
Gene Symbol:GLUD1 ( GDH,GDH1,GLUD,MGC132003 )
Gene Full Name: glutamate dehydrogenase 1
Band: 10q23.2
Quick LinksEntrez ID:2746; OMIM: 138130; Uniprot ID:DHE3_HUMAN; ENSEMBL ID: ENSG00000148672; HGNC ID: 4335
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
84N6-acetyllysine.
128Phosphoserine.
135Phosphotyrosine (By similarity).
227Phosphoserine (By similarity).
410Phosphothreonine.
450Phosphoserine (By similarity).
480N6-acetyllysine.
503N6-acetyllysine.
512Phosphotyrosine (By similarity).
527N6-acetyllysine (By similarity).
Location(AA) Modifications Resource
84N6-acetyllysine (By similarity).Swiss-Prot 53.0
227Phosphoserine (By similarity).Swiss-Prot 53.0
503N6-acetyllysine (By similarity).Swiss-Prot 53.0
527N6-acetyllysine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
23O-linkedHMM predict
26O-linkedHMM predict
144Phosphothreonine(CDC2)HMM predict
169Phosphothreonine(PKC)HMM predict
192N-linkedHMM predict
193Phosphotyrosine(INSR)HMM predict
196N-linkedHMM predict
206Phosphothreonine(PKA)HMM predict
261Phosphoserine(ATM)HMM predict
410Phosphothreonine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005271
  • Location:chr10 88800222-88844602
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 BcellGSE12603 88844249 88845129 880 87
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 88788377 88788909 532 11580
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 88835917 88835986 69 0
ER E2-MCF7GSE14664 88839369 88839402 33 0
FOXA1 MCF7GSE15244 88842162 88843032 870 0
FoxA1 MCF7MACSdata 88842451 88842699 248 0
H3K4me3 colorectalcancer 88842961 88843493 532 0
H3ac HepG2E 88840540 88843785 3245 0
Oct1 HelaGSE14283 88842585 88842628 43 0
PHF8 Hs68plusFBSGSE20725 88843302 88845769 2467 0
p130 shRbSenescentGSE19898 88844420 88844714 294 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
3422 EST chr10 88844245 88901462 280 mRNA GLUD1 chr10 88800224 88844603Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018