AutismKB 2.0

Annotation Detail for GMDS


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Basic Information Top
Gene Symbol:GMDS ( GMD,SDR3E1 )
Gene Full Name: GDP-mannose 4,6-dehydratase
Band: 6p25.3
Quick LinksEntrez ID:2762; OMIM: 602884; Uniprot ID:GMDS_HUMAN; ENSEMBL ID: ENSG00000112699; HGNC ID: 4369
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
38Phosphotyrosine(Jak)HMM predict
48Phosphotyrosine(Syk)HMM predict
59Phosphoserine(IKK)HMM predict
177Phosphoserine(CDC2)HMM predict
177Phosphoserine(CDK)HMM predict
224Phosphoserine(PKG)HMM predict
324Phosphotyrosine(Jak)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001500
  • Location:chr6 1569040-2190844
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 2191232 2191836 604 690
NFkBII GM10847GSE19485 2190144 2191813 1669 134
TFAP2C MCF7GSE21234 2191530 2191931 401 886
p130 SenescentGSE19898 2190990 2191378 388 340
p130 shRbQuiescentGSE19898 2191048 2191760 712 560
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 1564750 1565924 1174 3704
CTCF G2GSE9613 1566363 1566671 308 2524
NRSF mAbJurkat 1567544 1567872 328 1333
hScc1 BcellGSE12603 1564785 1565546 761 3875
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 1982806 1984112 1306 0
CTCF CD4GSE12889 2049521 2049873 352 0
CTCF CD4GSE12889 2141345 2141854 509 0
CTCF CD4GSE12889 2154598 2154791 193 0
CTCF CD4SISSRdata 2049521 2049873 352 0
CTCF CD4SISSRdata 2141345 2141854 509 0
CTCF CD4SISSRdata 2154598 2154791 193 0
CTCF JurkatGSE12889 2103815 2104166 351 0
CTCF G2GSE9613 1578819 1579147 328 0
CTCF G2GSE9613 1584351 1584576 225 0
CTCF G2GSE9613 1589069 1589503 434 0
CTCF G2GSE9613 1618264 1618557 293 0
CTCF G2GSE9613 1628116 1628319 203 0
CTCF G2GSE9613 1631387 1633188 1801 0
CTCF G2GSE9613 1678113 1678613 500 0
CTCF G2GSE9613 1725684 1725910 226 0
CTCF G2GSE9613 1726403 1726747 344 0
CTCF G2GSE9613 1733105 1733510 405 0
CTCF G2GSE9613 1814822 1815348 526 0
CTCF G2GSE9613 1860204 1860840 636 0
CTCF G2GSE9613 1919794 1919935 141 0
CTCF G2GSE9613 1940345 1940479 134 0
CTCF G2GSE9613 2141469 2141612 143 0
CTCF G2GSE9613 2142529 2142680 151 0
CTCF G2GSE9613 2145609 2147637 2028 0
CTCF G2GSE9613 2155625 2156002 377 0
CTCF G2GSE9613 2162263 2162551 288 0
CTCF G2GSE9613 2168469 2168719 250 0
CTCF G2GSE9613 2172947 2173154 207 0
CTCF G2GSE9613 2190239 2190919 680 0
ER Breast-CancerGSE22609 1586494 1587013 519 0
ER MCF7GSE19013 1585967 1587046 1079 0
ER MCF7GSE19013 1777881 1778686 805 0
ER MCF7GSE19013 1985682 1986181 499 0
FOXA1 MCF7GSE15244 1624605 1625887 1282 0
FOXA1 MCF7GSE15244 1669058 1669747 689 0
FOXA1 MCF7GSE15244 1783774 1785074 1300 0
Fos K562GSE19551 1575968 1576404 436 0
FoxA1 MCF7MACSdata 1784003 1784297 294 0
H3K4me2 HCT116GSE10453 2189639 2189990 351 0
H3K4me3 colorectalcancer 2189639 2190173 534 0
H3ac HepG2E 2172947 2173570 623 0
H3ac HepG2E 2187114 2189053 1939 0
H3ac HepG2E 2189639 2190383 744 0
KLF4 hESGSE17917 2190522 2190893 371 0
NFkBII GM12878GSE19485 1684162 1685869 1707 0
NFkBII GM12892GSE19485 1684247 1685664 1417 0
NFkBII GM15510GSE19485 1684455 1685665 1210 0
NFkBII GM18505GSE19485 1684580 1685574 994 0
NFkBII GM18526GSE19485 1684055 1685516 1461 0
Nanog ESGSE20650 2010176 2010463 287 0
Oct4 hESGSE17917 2103899 2104162 263 0
Oct4 hESGSE17917 2176160 2176368 208 0
P300 T30-glioblastomaGSE21026 1817800 1818311 511 0
P300 T30-glioblastomaGSE21026 1862562 1863467 905 0
P300 T30-glioblastomaGSE21026 1897621 1898706 1085 0
P300 T30-glioblastomaGSE21026 2181947 2182814 867 0
PHF8 293TGSE20725 2190134 2191493 1359 0
RARA MCF7GSE15244 1585874 1587253 1379 0
RARA MCF7GSE15244 1615568 1616559 991 0
RARA MCF7GSE15244 1624717 1625549 832 0
RARA MCF7GSE15244 1668872 1669887 1015 0
RARA MCF7GSE15244 1702290 1702937 647 0
RARA MCF7GSE15244 1783181 1784895 1714 0
RARA MCF7GSE15244 2189639 2190208 569 0
RARG MCF7GSE15244 1615175 1616524 1349 0
Rb GrowingGSE19898 1570642 1570792 150 0
Rb SenescentGSE19898 1570095 1570272 177 0
Rb shRbQuiescentGSE19898 1725871 1726052 181 0
Rb shRbSenescenceGSE19898 1953854 1954106 252 0
SRF HepG2GSE8489 2178357 2178592 235 0
STAT1 HeLaGSE12783 2181962 2183066 1104 0
TAF k562GSE8489 1683466 1683760 294 0
TFAP2C MCF7GSE21234 1586430 1587128 698 0
TFAP2C MCF7GSE21234 1615816 1616575 759 0
TFAP2C MCF7GSE21234 1627465 1627945 480 0
TFAP2C MCF7GSE21234 1668938 1669526 588 0
TFAP2C MCF7GSE21234 1706709 1707115 406 0
TFAP2C MCF7GSE21234 1783857 1784248 391 0
TFAP2C MCF7GSE21234 1840116 1840513 397 0
TFAP2C MCF7GSE21234 2049166 2049415 249 0
TFAP2C MCF7GSE21234 2107286 2107780 494 0
hScc1 BcellGSE12603 1569381 1570721 1340 0
hScc1 BcellGSE12603 1588337 1588694 357 0
hScc1 BcellGSE12603 1589376 1589576 200 0
hScc1 BcellGSE12603 1591479 1591619 140 0
hScc1 BcellGSE12603 1645079 1645367 288 0
hScc1 BcellGSE12603 1724026 1724230 204 0
hScc1 BcellGSE12603 1726403 1726825 422 0
hScc1 BcellGSE12603 1730793 1730930 137 0
hScc1 BcellGSE12603 1743745 1744071 326 0
hScc1 BcellGSE12603 1881591 1881805 214 0
hScc1 BcellGSE12603 1888086 1888402 316 0
hScc1 BcellGSE12603 2049538 2049853 315 0
hScc1 BcellGSE12603 2130705 2131091 386 0
hScc1 BcellGSE12603 2141321 2141688 367 0
hScc1 BcellGSE12603 2147148 2147557 409 0
hScc1 BcellGSE12603 2154464 2154897 433 0
hScc1 BcellGSE12603 2177967 2178108 141 0
hScc1 CdLSGSE12603 2049293 2049934 641 0
hScc1 CdLSGSE12603 2141164 2141896 732 0
hScc1 CdLSGSE12603 2154368 2155037 669 0
hScc1 G2GSE9613 2141280 2141688 408 0
p130 QuiescentGSE19898 1570677 1570901 224 0
p130 QuiescentGSE19898 1647381 1647572 191 0
p130 QuiescentGSE19898 2102670 2102907 237 0
p130 shRbQuiescentGSE19898 1569697 1570106 409 0
p63 keratinocytesGSE17611 1674331 1675503 1172 0
p63 keratinocytesGSE17611 1835203 1836055 852 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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