AutismKB 2.0

Annotation Detail for GNA11


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Basic Information Top
Gene Symbol:GNA11 ( GNA-11 )
Gene Full Name: guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
Band: 19p13.3
Quick LinksEntrez ID:2767; OMIM: 139313; Uniprot ID:GNA11_HUMAN; ENSEMBL ID: ENSG00000088256; HGNC ID: 4379
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
183ADP-ribosylarginine; by cholera toxin (By
Location(AA) Modifications Resource
183ADP-ribosylarginine; by cholera toxin (Bysimilarity).Swiss-Prot 53.0
Location(AA) Modification Resource
172Phosphotyrosine(Jak)HMM predict
222N-linkedHMM predict
266N-linkedHMM predict
332O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002067
  • Location:chr19 3045407-3072451
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 3031117 3032074 957 13812
Fos K562GSE19551 3045096 3045601 505 59
GABP k562GSE8489 3036223 3036360 137 9116
P300 T0-glioblastomaGSE21026 3031217 3031836 619 13881
P300 T30-glioblastomaGSE21026 3031185 3031923 738 13854
PHF8 HeLaGSE20725 3044725 3045981 1256 55
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 3076937 3077426 489 4730
CTCF CD4SISSRdata 3076937 3077426 489 4730
CTCF G2GSE9613 3076834 3077543 709 4737
hScc1 BcellGSE12603 3073218 3073842 624 1079
hScc1 BcellGSE12603 3076834 3077543 709 4737
p130 SenescentGSE19898 3076265 3076448 183 3905
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 3059760 3060063 303 0
CTCF CD4SISSRdata 3059760 3060063 303 0
CTCF G2GSE9613 3045661 3045801 140 0
CTCF G2GSE9613 3055117 3055800 683 0
CTCF G2GSE9613 3060166 3061292 1126 0
CTCF G2GSE9613 3067038 3067299 261 0
CTCF G2GSE9613 3068719 3069108 389 0
Myc K562GSE19551 3059717 3060194 477 0
PHF8 293TGSE20725 3044611 3046475 1864 0
hScc1 BcellGSE12603 3045661 3046062 401 0
hScc1 BcellGSE12603 3055117 3055370 253 0
hScc1 BcellGSE12603 3060471 3060963 492 0
hScc1 BcellGSE12603 3068719 3069108 389 0
hScc1 CdLSGSE12603 3055117 3055669 552 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018